Know more

About cookies

What is a "cookie"?

A "cookie" is a piece of information, usually small and identified by a name, which may be sent to your browser by a website you are visiting. Your web browser will store it for a period of time, and send it back to the web server each time you log on again.

Different types of cookies are placed on the sites:

  • Cookies strictly necessary for the proper functioning of the site
  • Cookies deposited by third party sites to improve the interactivity of the site, to collect statistics

Learn more about cookies and how they work

The different types of cookies used on this site

Cookies strictly necessary for the site to function

These cookies allow the main services of the site to function optimally. You can technically block them using your browser settings but your experience on the site may be degraded.

Furthermore, you have the possibility of opposing the use of audience measurement tracers strictly necessary for the functioning and current administration of the website in the cookie management window accessible via the link located in the footer of the site.

Technical cookies

Name of the cookie


Shelf life

CAS and PHP session cookies

Login credentials, session security



Saving your cookie consent choices

12 months

Audience measurement cookies (AT Internet)

Name of the cookie


Shelf life


Trace the visitor's route in order to establish visit statistics.

13 months


Store the anonymous ID of the visitor who starts the first time he visits the site

13 months


Identify the numbers (unique identifiers of a site) seen by the visitor and store the visitor's identifiers.

13 months

About the AT Internet audience measurement tool :

AT Internet's audience measurement tool Analytics is deployed on this site in order to obtain information on visitors' navigation and to improve its use.

The French data protection authority (CNIL) has granted an exemption to AT Internet's Web Analytics cookie. This tool is thus exempt from the collection of the Internet user's consent with regard to the deposit of analytics cookies. However, you can refuse the deposit of these cookies via the cookie management panel.

Good to know:

  • The data collected are not cross-checked with other processing operations
  • The deposited cookie is only used to produce anonymous statistics
  • The cookie does not allow the user's navigation on other sites to be tracked.

Third party cookies to improve the interactivity of the site

This site relies on certain services provided by third parties which allow :

  • to offer interactive content;
  • improve usability and facilitate the sharing of content on social networks;
  • view videos and animated presentations directly on our website;
  • protect form entries from robots;
  • monitor the performance of the site.

These third parties will collect and use your browsing data for their own purposes.

How to accept or reject cookies

When you start browsing an eZpublish site, the appearance of the "cookies" banner allows you to accept or refuse all the cookies we use. This banner will be displayed as long as you have not made a choice, even if you are browsing on another page of the site.

You can change your choices at any time by clicking on the "Cookie Management" link.

You can manage these cookies in your browser. Here are the procedures to follow: Firefox; Chrome; Explorer; Safari; Opera

For more information about the cookies we use, you can contact INRAE's Data Protection Officer by email at or by post at :


24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo Principal NutriNeurO logo partenaire Logo Bx INP

NutriNeuro: Integrated Nutrition and Neurobiology Lab

Zone de texte éditable et éditée et rééditée

Psychoneuroimmunology and Nutrition publications 2005-2021

2021202020192018 - 2017 - 2016 2015 - 2014 - 2013 - 2012 - 2011 - 2010 - 2009 - 2008 - 2007 -2006 - 2005


Allichon MC, Ortiz V, Pousinha P, Andrianarivelo A, Petitbon A, Heck N, Trifilieff P, Barik J, Vanhoutte P. Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse. Front Synaptic Neurosci 13, 799274. doi:10.3389/fnsyn.2021.799274

Andrianarivelo, A., Saint-Jour, E., Pousinha, P., Fernandez, S.P., Petitbon, A., De Smedt-Peyrusse, V., Heck, N., Ortiz, V., Allichon, M.-C., Kappès, V., Betuing, S., Walle, R., Zhu, Y., Joséphine, C., Bemelmans, A.-P., Turecki, G., Mechawar, N., Javitch, J.A., Caboche, J., Trifilieff, P., Barik, J., Vanhoutte, P., 2021. Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine’s rewarding effects but preserves natural reward processing. Sci Adv 7, eabg5970. doi:10.1126/sciadv.abg5970

Biyong EF, Alfos S, Dumetz F, Helbling JC, Aubert A, Brossaud J, Foury A, Moisan MP, Layé S, Richard E, Patterson E, Murphy K, Rea K, Stanton C, Schellekens H, Cryan JF, Capuron L, Pallet V, Ferreira G (2021). Dietary vitamin A supplementation prevents early obesogenic diet-induced microbiota, neuronal and cognitive alterations. Int J Obes (Lond) 45(3):588-598. doi: 10.1038/s41366-020-00723-z.

Branchi I, Poggini S, Capuron L, Benedetti F, Poletti S, Tamouza R, Drexhage HA, Penninx BWJH, Pariante CM; European College of Neuropsychopharmacology (ECNP) ImmunoNeuroPsychiatry Thematic Working Group and Marion Leboyer (2021). Brain-immune crosstalk in the treatment of major depressive disorder. Eur Neuropsychopharmacol 45:89-107. doi: 10.1016/j.euroneuro.2020.11.016.

Chataigner M, Mortessagne P, Lucas C, Pallet V, Layé S, Mehaignerie A, Bouvret E, Dinel AL, Joffre C (2021). Dietary fish hydrolysate supplementation containing n-3 LC-PUFAs and peptides prevents short-term memory and stress response deficits in aged mice. Brain Behav Immun 91:716-730. doi: 10.1016/j.bbi.2020.09.022.

Chataigner M, Martin M, Lucas C, Pallet V, Layé S, Mehaignerie A, Bouvret E, Dinel AL, Joffre C (2021). Fish Hydrolysate Supplementation Containing n-3 Long Chain Polyunsaturated Fatty Acids and Peptides Prevents LPS-Induced Neuroinflammation. Nutrients 13(3):824. doi: 10.3390/nu13030824.

Clayton K, Delpech JC, Herron S, Iwahara N, Ericsson M, Saito T, Saido TC, Ikezu S, Ikezu T (2021). Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model. Mol Neurodegener 16(1):18. doi: 10.1186/s13024-021-00440-9.

Clayton K, Delpech JC, Herron S, Iwahara N, Ericsson M, Saito T, Saido TC, Ikezu S, Ikezu T (2021). Correction to: Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model. Mol Neurodegener 16(1):24. doi: 10.1186/s13024-021-00447-2.

Consoloni JL, M'Bailara K, Perchec C, Aouizerate B, Aubin V, Azorin JM, Bellivier F, Correard N, Courtet P, Dubertret C, Etain B, Gard S, Haffen E, Leboyer M, Llorca PM, Olié E, Polosan M, Roux P, Schwan R, Samalin L, Belzeaux R; Groupe FACE-BD (2021). Trajectories of medication adherence in patients with Bipolar Disorder along 2 years-follow-up. J Affect Disord 282:812-819. doi: 10.1016/j.jad.2020.12.192.

Cussotto S, Aouizerate B, Capuron L.(2021). From gut to brain: Microbiota depletion in mice as a tool to explore causality. Brain Behav Immun 94:4-5. doi: 10.1016/j.bbi.2021.02.029.

De Meij J, Alfanek Z, Morel L, Decoeur F, Leyrolle Q, Picard K, Carrier M, Aubert A, Séré A, Lucas C, Laforest G, Helbling JC, Tremblay ME, Cota D, Moisan MP, Marsicano G, Layé S, Nadjar A (2021). Microglial cannabinoid type 1 receptor regulates brain inflammation in a sex-specific manner. Cannabis Cannabinoid Res. Sep 29. doi: 10.1089/can.2020.0170.

Delgado I, Dexpert S, Sauvant JCryan JFCapuron L (2021). Influence of pro-obesogenic dietary habits on stress-induced cognitive alterations in healthy adult volunteers. Neurobiology Stress 15:100353. doi: 10.1016/j.ynstr.2021.100353.

Delpech JC, Pathak D, Varghese M, Kalavai SV, Hays EC, Hof PR, Johnson WE, Ikezu S, Medalla M, Luebke JI, Ikezu T. Wolframin-1-expressing neurons in the entorhinal cortex propagate tau to CA1 neurons and impair hippocampal memory in mice. Sci Transl Med. 2021 Sep 15;13(611):eabe8455. doi: 10.1126/scitranslmed.abe8455. Epub 2021 Sep 15. PMID: 34524859.

Ducrocq F, Trifilieff P (2021). [Motivational deficits and polyunsaturated fatty acids]. Med Sci (Paris) 37(1):15-18. doi: 10.1051/medsci/2020250.

Etain B, Bellivier F, Olié E, Aouizerate B, Aubin V, Belzeaux R, Courtet P, Dubertret C, Schwan R, Roux P, Polosan M, Leboyer M, Godin O; FondaMental Advanced Center of Expertise for Bipolar Disorders (FACE-BD); FACE-BD Clinical Sites and Principal Collaborators in France (2021). Clinical predictors of recurrences in bipolar disorders type 1 and 2: A FACE-BD longitudinal study. J Psychiatr Res 134:129-137. doi: 10.1016/j.jpsychires.2020.12.041.

Fanet H, Tournissac M, Leclerc M, Caron V, Tremblay C, Vancassel S, Calon F (2021). Tetrahydrobiopterin Improves Recognition Memory in the Triple-Transgenic Mouse Model of Alzheimer's Disease, Without Altering Amyloid-β and Tau Pathologies. J Alzheimers Dis 79(2):709-727. doi: 10.3233/JAD-200637.

Felger JC, Capuron L (2021). Special Issue: The intersection of inflammation and metabolism in neuropsychiatric disorders. Brain Behav Immun 93:331-334. doi: 10.1016/j.bbi.2020.12.025.

Galera C, Barbosa S, Collet O, Khalfallah O, Aouizerate B, Sutter-Dalley AL, Koehl M, Capuron L, Van der Waerden J, Melchior M, Côté S, Heude B, Glaichenhaus N, Davidovic L; EDEN Mother–Child Cohort Study Group (2021). Cord Serum Cytokines at Birth and Children's Anxiety-Depression Trajectories From 3 to 8 Years: The EDEN Mother-Child Cohort. Biol Psychiatry 89(6):541-549. doi: 10.1016/j.biopsych.2020.10.009.

Helbling JC, Kinouchi K, Trifilieff P, Sassone-Corsi P, Moisan MP (2021). Combined Gene Expression and Chromatin Immunoprecipitation From a Single Mouse Hippocampus. Curr Protoc 1(2):e33. doi: 10.1002/cpz1.33.

Huet L, Delgado I, Dexpert S, Sauvant J, Aouizerate B, Beau C, Forestier D, Ledaguenel P, Magne E, Capuron L.(2021). Relationship between body mass index and neuropsychiatric symptoms: Evidence and inflammatory correlates. Brain Behav Immun 94:104-110. doi: 10.1016/j.bbi.2021.02.031.

Ikezu S, Yeh H, Delpech JC, Woodbury ME, Van Enoo AA, Ruan Z, Sivakumaran S, You Y, Holland C, Guillamon-Vivancos T, Yoshii-Kitahara A, Botros MB, Madore C, Chao PH, Desani A, Manimaran S, Kalavai SV, Johnson WE, Butovsky O, Medalla M, Luebke JI, Ikezu T. Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities. Mol Psychiatry. 2021 Jun;26(6):1808-1831. doi: 10.1038/s41380-020-0671-2. Epub 2020 Feb 18. PMID: 32071385; PMCID: PMC7431382.

Jackson PA, Forster J, Khan J, Pouchieu C, Dubreuil S, Gaudout D, Moras B, Pourtau L, Joffre F, Vaysse C, Bertrand K, Abrous H, Vauzour D, Brossaud J, Corcuff JB, Capuron L, Kennedy DO (2021). Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial. Front Nutr 7:606124. doi: 10.3389/fnut.2020.606124.

Khoury M, Chamsine S, Merheb C, Arfoul E, Rached M, Younes F, El Osta N, Laye S, Aoun C, Papazian T, Rabbaa Khabbaz L (2021). Binge eating among young adults: association with sociodemographic factors, nutritional intake, dietary n-6: n-3 ratio and impulsivity. Br J Nutr. 14:1-10. doi: 10.1017/S0007114521000118

Martinat M, Rossitto M, Di Miceli M, Layé S (2021). Perinatal dietary polyunsaturated fatty acids in brain dvelopment, role in neurodevelopmental disorders. Nutrients 13(4):1185. doi: 10.3390/nu13041185.

Moisan MP, Foury A, Dexpert S, Cole SW, Beau C, Forestier D, Ledaguenel P, Magne E, Capuron L (2021). Transcriptomic signaling pathways involved in a naturalistic model of inflammation-related depression and its remission. Transl Psychiatry 11(1):203. doi: 10.1038/s41398-021-01323-9.

Monchaux De Oliveira C, Pourtau L, Vancassel S, Pouchieu C, Capuron L, Gaudout D, Castanon N. (2021). Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission. Nutrients 13(3):904. doi: 10.3390/nu13030904.

Neiers F, Jarriault D, Menetrier F, Briand L, Heydel JM (2021). The odorant metabolizing enzyme UGT2A1: Immunolocalization and impact of the modulation of its activity on the olfactory response. PLoS One 16(3):e0249029. doi: 10.1371/journal.pone.0249029.

Nobile B, Dubois J, Aouizerate B, Aubin V, Loftus J, Bellivier F, Belzeaux R, Dubertret C, Gard S, Haffen E, Schwan R, Llorca PM, Passerieux C, Roux P, Polosan M, Etain B, Leboyer M; FondaMental Advanced Centres of Expertise in Bipolar Disorders (FACE-BD) Collaborators, Courtet P, Olié E (2021). Characterization of depressed bipolar patients with current suicidal ideation. Aust N Z J Psychiatry 55(3):289-304. doi: 10.1177/0004867420963744.

Sunhary de Verville PL, Etchecopar-Etchart D, Richieri R, Godin O, Schürhoff F, Berna F, Aouizerate B, Capdevielle D, Chereau I, D'Amato T, Dubertret C, Dubreucq J, Leignier S, Mallet J, Misdrahi D, Passerieux C, Pignon B, Rey R, Urbach M, Vidailhet P, Leboyer M, Llorca PM, Lançon C, Boyer L, Fond G; FACE-SZ (FondaMental Academic Centers of Expertise for Schizophrenia) group (2021). Recommendations of the schizophrenia expert center network for the screening prevention and treatment of sleep disorders based on the results from the real-world schizophrenia FACE-SZ national cohort. Prog Neuropsychopharmacol Biol Psychiatry 110:110275. doi: 10.1016/j.pnpbp.2021.110275.

Yrondi A, Arbus C, Bennabi D, D'Amato T, Bellivier F, Bougerol T, Camus V, Courtet P, Doumy O, Genty JB, Holtzmann J, Horn M, Lancon C, Leboyer M, Llorca PM, Maruani J, Moirand R, Molière F, Petrucci J, Richieri R, Samalin L, Stephan F, Vaiva G, Walter M; FondaMental Advanced Centres of Expertise in Resistant Depression (FACE-DR) Collaborators, Haffen E, Aouizerate B, El-Hage W (2021). Relationship between childhood physical abuse and clinical severity of treatment-resistant depression in a geriatric population. PLoS One 16(4):e0250148. doi: 10.1371/journal.pone.0250148.

Yrondi A, Vaiva G, Walter M, D Amato T, Bellivier F, Bennabi D, Bougerol T, Camus V, Doumy O, Genty JB, Haffen E, Holtzmann J, Horn M, Lançon C, Leboyer M, Llorca PM, Maruani J, Moirand R, Molière F, Petrucci J, Richieri R, Samalin L, Schmitt L, Stephan F; FondaMental Advanced Centers of Expertise in Resistant Depression (FACE-DR), Courtet P, El-Hage W, Aouizerate B; List of FondaMental Advanced Centre of Expertise (FACE-DR) collaborators; FACE-DR Clinical Sites and Principal Collaborators in France (2021). Childhood Trauma increases suicidal behaviour in a treatment-resistant depression population: a FACE-DR report. J Psychiatr Res 135:20-27. doi: 10.1016/j.jpsychires.2020.12.055.


Ruan Z, Delpech JC, Venkatesan Kalavai S, Van Enoo AA, Hu J, Ikezu S, Ikezu T. P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice. Mol Neurodegener. 2020 Aug 18;15(1):47. doi: 10.1186/s13024-020-00396-2. PMID: 32811520; PMCID: PMC7436984.

Madore C, Leyrolle Q, Morel L, Rossitto M, Greenhalgh AD, Delpech JC, Martinat M, Bosch-Bouju CBourel J, Rani B, Lacabanne C, Thomazeau A, Hopperton KE, Beccari S, Sere A, Aubert A, De Smedt-Peyrusse V, Lecours C, Bisht K, Fourgeaud L, Gregoire S, Bretillon L, Acar N, Grant NJ, Badaut J, Gressens P, Sierra A, Butovsky O, Tremblay ME, Bazinet RP, Joffre C, Nadjar A, Layé S (2020). Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain. Nat Commun 11(1):6133. doi: 10.1038/s41467-020-19861-z.

Fanet H, Capuron L, Castanon N, Calon F, Vancassel S (2020). Tetrahydrobioterin (BH4) pathway: from metabolism to neuropsychiatry. Curr Neuropharmacol Jul 28. doi: 10.2174/1570159X18666200729103529.

Germain V, Scherlinger M, Barnetche T, Pichon C, Balageas A, Lequen L, Shipley E, Foret J, Dublanc S, Capuron L, Schaeverbeke T (2020). Role of stress in the development of rheumatoid arthritis: a case-control study. Rheumatology (Oxford) Jun 13:keaa216. doi: 10.1093/rheumatology/keaa216.

Cussotto S, Delgado I, Anesi A, Dexpert S, Aubert A, Beau C, Forestier D, Ledaguenel P, Magne E, Mattivi F, Capuron L (2020). Tryptophan metabolic pathways are altered in obesity and are associated with systemic inflammation. Front Immunol. 2020 Apr 15;11:557. doi: 10.3389/fimmu.2020.00557.

Al Abed AS, Sellami A, Potier M, Ducourneau EG, Gerbeaud-Lassau P, Brayda-Bruno L, Lamothe V, Sans N, Desmedt A, Vanhoutte P, Bennetau-Pelissero C, Trifilieff P, Marighetto A (2020). Age-related impairment of declarative memory: linking memorization of temporal associations to GluN2B redistribution in dorsal CA1. Aging Cell 19: e13243. doi: 10.1111/acel.13243.

Chataigner M, Mortessagne P, Lucas C, Pallet V, Layé S, Mehaignerie A, Bouvret E, Dinel AL, Joffre C. (2020). Dietary fish hydrolysate supplementation containing n-3 LC-PUFAs and peptides prevents short-term memory and stress response deficits in aged mice. Brain Behav Immun Sep 23:S0889-1591(20)30743-1. doi: 10.1016/j.bbi.2020.09.022.

Di Miceli M, Husson Z, Ruel P, Layé S, Cota D, Fioramonti X, Bosch-Bouju C, Gronier B. (2020). In silico hierarchical clustering of neuronal populations in the rat ventral tegmental area based on extracellular electrophydriological properties. Front Neural Circuits 14:51. doi: 10.3389/fncir.2020.00051.

Lin L, Metherel AH, Di Miceli M, Liu Z, Sahin C, Fioramonti X, Cummins CL, Layé S, Bazinet RP. (2020). Tetracosahexaenoylethanolamide, a novel N-acylethanolamide, is elevated in ischemia and increases neuronal output. J Lipid Res 61: 1480-1490. doi: 10.1194/jlr.RA120001024.

Leyrolle Q, Decoeur F, Briere G, Amadieu C, Quadros ARAA, Voytyuk I, Lacabanne C, Benmamar-Badel A, Bourel J, Aubert A, Sere A, Chain F, Schwendimann L, Matrot B, Bourgeois T, Grégoire S, Leblanc JG, De Moreno De Leblanc A, Langella P, Fernandes GR, Bretillon L, Joffre C, Uricaru R, Thebault P, Gressens P, Chatel JM, Layé S, Nadjar A. (2020). Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime. Neuropsychopharmacology Aug 11. doi: 10.1038/s41386-020-00793-7.

Di Miceli M, Bosch-Bouju C, Layé S. (2020). PUFA and their derivatives in neurotransmission and synapses: a new hallmark of synaptopathies. Proc Nutr Soc Apr 17:1-16. doi: 10.1017/S0029665120000129.

Berland C, Montalban E, Perrin E, Di Miceli M, Nakamura Y, Martinat M, Sullivan M, Davis XS, Shenasa MA, Martin C, Tolu S, Marti F, Caille S, Castel J, Perez S, Salinas CG, Morel C, Hecksher-Sørensen J, Cador M, Fioramonti X, Tschöp MH, Layé S, Venance L, Faure P, Hnasko TS, Small DM, Gangarossa G, Luquet SH (2020). Circulating triglycerides gate dopamine-associated behaviors through DRD2-expressing neurons. Cell Metab 31: 773-790. doi: 10.1016/j.cmet.2020.02.010.

Dinel AL., Lucas C., Guillemet D., Layé S., Pallet V., Joffre C. (2020). Chronic supplementation with a mix of Salvia officials and Salvia lavandulaefolia improves Morris water maze learning in normal adult C57Bl/6J mice. Nutrients 12: 1777. doi: 10.3390/nu12061777.

Ducrocq F., Walle R., Contini A., Oummadi A., Caraballo B., Van Der Veldt S., Boyer M.-L., Aby F., Tolentino-Cortez T., Helbling J.-C., Martine L., Grégoire S., Cabaret S., Vancassel S., Layé S., Kang J. X., Fioramonti X., Berdeaux O., Barreda-Gómez Masson E., Ferreira G., Ma D. W. L., Bosch-Bouju C., De Smedt-Peyrusse V., Trifilieff P. (2020). Causal link between n-3 polyunsaturated fatty acid deficiency and motivation deficits. Cell Metabolism, 31(4):755-772.e7. doi: 10.1016/j.cmet.2020.02.012.

Fanet H, Ducrocq FTournissac M, Oummadi A, Lo A, Bourrassa P, De Smedt-Peyrusse V, Azzougen B, Capuron L, Layé S, Moussa F, Trifilieff P, Calon F, Vancassel S. (2020) Tetrahydrobiopterin administration facilitates amphetamine-induced dopamine release and motivation in mice. Behav Brain Res. Nov 8:112348. doi: 10.1016/j.bbr.2019.112348.

Inczefi O, Bacquié V., Olier-Pierre M, Rincel M., Ringet-destrez B, Ellers-Simatos S, Eutamène H, Bétoulières C, Thomas JLaine J, Gros L, Lévêque M, Leonard R, Harkat C, Robbe-Masselot C, Roka R, Mercier-Bonin M, Theodorou V, Darnaudéry M, Turner JR, Ferrier L. (2020) Targeted intestinal tight junction hyper permeability alters the microbiome, behavior, and visceromotor responses. Cell Mol Gastroenterol Heppatol Mar 6. pii: S2352-345X(20)30035-7. doi: 10.1016/j.jcmgh.

Joffre C., Dinel A.L., Chataigner M., Pallet V., Layé S. (2020). N-3 polyunsaturated fatty acids and their derivates reduce neuroinflammation during aging. Nutrients, 12:647. doi: 10.3390/nu12030647.

 Zhu Y., Dwork A.J., Trifilieff P., Javitch J.A. (2020). Detection of G Protein-Coupled Receptor Complexes in Postmortem Human Brain by Proximity Ligation Assay. Curr Protoc Neurosci. 91:e86. doi: 10.1002/cpns.86.

Albaret G, Sifré E, Floch P, Laye S, Aubert A, Dubus P, Azzi-Martin L, Giese A, Salles N, Mégraud F, Varon C, Lehours P, Roubaud-Baudron C (2020). Alzheimer's disease and helicobacter pylori: inflammation from stomach to brain? J Alzheimers Dis 73: 801-809. doi: 10.3233/JAD-190496.

Bogdanov VB, Bogdanova OV, Dexpert S, Delgado I, Beyer H, Aubert A, Dilharreguy B, Beau C, Forestier D, Ledaguenel P, Magne E, Aouizerate B, Layé S, Ferreira G, Felger J, Pagnoni G, Capuron L. (2020). Reward-related brain activity and behavior are associated with peripheral gherkin levels in obesity. Psychoneuroendocrinology 112: 104520. doi: 10.1016/j.psyneuen.2019.104520.

Fourrier C, Kropp C, Aubert A, Sauvant J, Vaysse C, Chardigny JM, Layé S, Joffre C, Castanon N (2020). Rapeseed oil fortified with micronutrients improves cognitive alterations associated with metabolic syndrome. Brain Behav Immun. 84:23-35. doi: 10.1016/j.bbi.2019.11.002.

Bazinet RP, Metherel AH, Chen CT, Shaikh SR, Nadjar A, Joffre C, Layé S (2020)Brain eicosapentaenoic acid metabolism as a lead for novel therapeutics in major depression. Brain Behav Immun. 85:21-28. doi: 10.1016/j.bbi.2019.07.001.

Decoeur F, Benmamar-Badel A, Leyrolle Q, Persillet M, Layé S, Nadjar A (2020). Dietary N-3 PUFA deficiency affects sleep-wake activity in basal condition and in response to an inflammatory challenge in mice. Brain Behav Immun. 85:162-169. doi: 10.1016/j.bbi.2019.05.016.

Quarta C, Fioramonti X, Cota D (2020). POMC Neurons Dysfunction in Diet-induced Metabolic Disease: Hallmark or Mechanism of Disease? Neuroscience 447: 3-14. doi: 10.1016/j.neuroscience.2019.09.031.


Dinel AL, Guinobert I, Lucas C., Blondeau C., Bardot V., Ripoche I, Berthomier L, Pallet, V., Layé S., Joffre C (2019). Reduction of acute mild stress corticosterone response and changes in stress-responsive gene expression in male Balb/c mice after repeated administration of a Rhodiola rosea L. root extract. Food Sci Nutr 7: 3827-3841. doi: 10.1002/fsn3.1249

Salery M, Trifilieff P, Caboche J, Vanhoutte P. (2019) From Signaling Molecules to Circuits and Behaviors: Cell-Type-Specific Adaptations to Psychostimulant Exposure in the Striatum. Biol Psychiatry. Nov 9. pii: S0006-3223(19)31849-9. doi: 10.1016/j.biopsych.2019.11.001. 

 Zhu Y, Mészáros J, Walle R, Fan R, Sun Z, Dwork AJ, Trifilieff P, Javitch JA.  (2019) Detecting G protein-coupled receptor complexes in postmortem human brain with proximity ligation assay and a Bayesian classifier. Biotechniques 68: 122-129. doi: 10.2144/btn-2019-0083. 

 Fernández R, Garate J, Tolentino-Cortez T, Herraiz A, Lombardero L, Ducrocq F, Rodríguez-Puertas R, Trifilieff P, Astigarraga E, Barreda-Gómez G, Fernández JA.  (2019) Microarray and Mass Spectrometry-Based Methodology for Lipid Profiling of Tissues and Cell Cultures. Anal Chem. 91:15967-15973. doi: 10.1021/acs.analchem.9b04529.

Aouizerate B, El-Hage W. [Only good therapeutic strategies! Response to the letter about the special issue: "All the truth about benzodiapzepines"]. Presse Med. 2019;48:217-218.

Aouizerate B, Haffen E. New Research in Obsessive-Compulsive Disorder and Major Depression. Brain Sci. 2019;9.

Bennabi D, Charpeaud T, Yrondi A, Genty JB, Destouches S, Lancrenon S, Alaili N, Bellivier F, Bougerol T, Camus V, Dorey JM, Doumy O, Haesebaert F, Holtzmann J, Lancon C, Lefebvre M, Moliere F, Nieto I, Rabu C, Richieri R, Schmitt L, Stephan F, Vaiva G, Walter M, Leboyer M, El-Hage W, Llorca PM, Courtet P, Aouizerate B, Haffen E. Clinical guidelines for the management of treatment-resistant depression: French recommendations from experts, the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental. BMC Psychiatry. 2019;19:262.

Bennabi D, Yrondi A, Charpeaud T, Genty JB, Destouches S, Lancrenon S, Allaili N, Bellivier F, Bougerol T, Camus V, Doumy O, Dorey JM, Haesebaert F, Holtzmann J, Lancon C, Lefebvre M, Moliere F, Nieto I, Rabu C, Richieri R, Schmitt L, Stephan F, Vaiva G, Walter M, Leboyer M, El-Hage W, Aouizerate B, Haffen E, Llorca PM, Courtet P. Clinical guidelines for the management of depression with specific comorbid psychiatric conditions French recommendations from experts (the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental). BMC Psychiatry. 2019;19:50.

Brunet-Gouet E, Myszkowski N, Ehrminger M, Urbach M, Aouizerate B, Brunel L, Capdevielle D, Chereau I, Dubertret C, Dubreucq J, Fond G, Lancon C, Leignier S, Mallet J, Misdrahi D, Pires S, Schneider P, Schurhoff F, Yazbek H, Zinetti-Bertschy A, Bazin N, Passerieux C, Zenasni F, Roux P. Confirmation of a Two-Factor Solution to the Questionnaire of Cognitive and Affective Empathy in a French Population of Patients With Schizophrenia Spectrum Disorders. Front Psychiatry. 2019;10:751.

Ehrminger M, Urbach M, Passerieux C, Aouizerate B, Berna F, Bohec AL, Capdevielle D, Chereau I, Clauss J, Dubertret C, Esselin A, Faget C, Fond G, Honciuc RM, Jarroir M, Mallet J, Misdrahi D, Pignon B, Rey R, Schurhoff F, Yazbek H, Brunet-Gouet E, Roux P. Modeling the Longitudinal Effects of Insight on Depression, Quality of Life and Suicidality in Schizophrenia Spectrum Disorders: Results from the FACE-SZ Cohort. J Clin Med. 2019;8.

Fond G, Bulzacka E, Boucekine M, Schurhoff F, Berna F, Godin O, Aouizerate B, Capdevielle D, Chereau I, D'Amato T, Dubertret C, Dubreucq J, Faget C, Leignier S, Lancon C, Mallet J, Misdrahi D, Passerieux C, Rey R, Schandrin A, Urbach M, Vidailhet P, Leboyer M, group F-S, Boyer L, Llorca PM. Machine learning for predicting psychotic relapse at 2years in schizophrenia in the national FACE-SZ cohort. Prog Neuropsychopharmacol Biol Psychiatry. 2019;92:8-18.

Fond G, Godin O, Boyer L, Berna F, Andrianarisoa M, Coulon N, Brunel L, Bulzacka E, Aouizerate B, Capdevielle D, Chereau I, D'Amato T, Dubertret C, Dubreucq J, Faget C, Leignier S, Lancon C, Mallet J, Misdrahi D, Passerieux C, Rey R, Schandrin A, Urbach M, Vidailhet P, Llorca PM, Schurhoff F, Leboyer M, Group F-S. Chronic low-grade peripheral inflammation is associated with ultra resistant schizophrenia. Results from the FACE-SZ cohort. Eur Arch Psychiatry Clin Neurosci. 2019;269:985-992.

Fond G, Godin O, Dumontaud M, Faget C, Schurhoff F, Berna F, Aouizerate B, Capdevielle D, Chereau I, D'Amato T, Dubertret C, Dubreucq J, Leignier S, Mallet J, Misdrahi D, Passerieux C, Rey R, Schandrin A, Szoke A, Urbach M, Vidailhet P, Leboyer M, Lancon C, Boyer L, Llorca PM, group F-S. Sexual dysfunctions are associated with major depression, chronic inflammation and anticholinergic consumption in the real-world schizophrenia FACE-SZ national cohort. Prog Neuropsychopharmacol Biol Psychiatry. 2019;94:109654.

Garofalo S, Picard K, Limatola C, Nadjar A, Pascual O, Tremblay ME. Role of glia in the regulation of sleep in health and disease. Comprehensive Physiol 2019.

Joffre C, Rey C, Layé S (2019). N-3 Polyunsaturated Fatty Acids and the Resolution of Neuroinflammation. Front Pharmacol. 10:1022. doi: 10.3389/fphar.2019.01022.

Oriolo G, Blanco-Hinojo L, Navines R, Mariño Z, Martín-Hernández D, Cavero M, Gimenez D, Caso J, Capuron L, Forns X, Pujol J, Sola R, Martin-Santos R (2019). Association of chronic inflammation and perceived stress with abnormal functional connectivity in brain areas involved with interoception in hepatitis C patients. Brain Behav Immun. 80:204-218. doi: 10.1016/j.bbi.2019.03.008.

Rincel M, Aubert P, Chevalier J, Grohard PA, Basso L, Monchaux de Oliveira CMHelbling JC, Lévy É, Chevalier G, Leboyer M, Eberl G, Layé S, Capuron L, Vergnolle N, Neunlist M, Boudin H, Lepage P, Darnaudéry M (2019). Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner. Brain Behav Immun. 80:179-192. doi: 10.1016/j.bbi.2019.03.006.

Zemdegs J, Martin H, Pintana H, Bullich S, Manta S, Marqués MA, Moro C, Layé S, Ducrocq F, Chattipakorn N, Chattipakorn SC, Rampon C, Pénicaud L, Fioramonti X, Guiard BP (2019). Metformin Promotes Anxiolytic and Antidepressant-Like Responses in Insulin-Resistant Mice by Decreasing Circulating Branched-Chain Amino Acids. J Neurosci. 39(30):5935-5948. doi: 10.1523/JNEUROSCI.2904-18.2019.

Andrianarivelo A, Saint-Jour E, Walle R, Trifilieff P, Vanhoutte P (2019). Modulation and functions of dopamine receptor heteromers in drugs of abuse-induced adaptations. Neuropharmacology. 152:42-50. doi: 10.1016/j.neuropharm.2018.12.003.

Leyrolle Q, Layé S, Nadjar N (2019). Direct and indirect effects of lipids on microglia function. Neurosci Lett. 708:134348. doi: 10.1016/j.neulet.2019.134348.

Rincel M, Darnaudéry M (2019). Maternal separation in rodents: a journey from gut to brain and nutritional perspectives. Proc Nutr Soc.  28:1-20. doi: 0.1017/S0029665119000958.

Rincel M, Olier M, Minni A, de Oliveira CM, Matime Y, Gaultier E, Grit I, Helbling JC, Costa AM, Lépinay A, Moisan MP, Layé S, Ferrier L, Parnet P, Theodorou V, Darnaudéry M (2019). Pharmacological restoration of gut barrier function in stressed neonates partially reverses long-term alterations associated with maternal separation. Psychopharmacology (Berl). 236(5):1583-1596. doi: 10.1007/s00213-019-05252-w.

Bouyakdan K, Martin H, Liénard F, Budry L, Rodaros D, Chrétien C, Bidon E, Husson Z, Cota D, Pénicaud L, Fulton S, Fioramonti X, Alquier T (2019). The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin systemJ Clin Invest. 2019 Apr 2;130:2417-2430. doi: 10.1172/JCI123454.

Fourrier C, Bosch-Bouju C, Boursereau R, Sauvant J, Aubert A, Capuron L, Ferreira G, Layé SCastanon N. Brain tumor necrosis factor-alpha mediates anxiety-like behavior in a mouse model of severe obesity. Brain Behav Immun. 277:25-36. doi: 10.1016/j.bbi.2018.11.316.

Oriolo G, Huet L, Dexpert S, Beau C, Forestier D, Ledaguenel P, Magne E, Martin-Santos R, Capuron L (2019). History of major depression is associated with neuropsychiatric symptoms but not systemic inflammation in a cross-sectional study in obese patients. Brain Behav Immun. 76:215-222. doi: 10.1016/j.bbi.2018.11.312.

Cruciani-Guglielmacci C, Fioramonti X (2019). Editorial: Brain Nutrient Sensing in the Control of Energy Balance: New Insights and Perspectives. Front Physiol. 10:51. doi: 10.3389/fphys.2019.00051.

Desmoulins L, Chrétien C, Paccoud R, Collins S, Cruciani-Guglielmacci C, Galinier A, Liénard F, Quinault A, Grall S, Allard C, Fenech C, Carneiro L, Mouillot T, Fournel A, Knauf C, Magnan C, Fioramonti X, Pénicaud L, Leloup C (2019). Mitochondrial Dynamin-Related Protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing. Mol Metab. 20:166-177. doi: 10.1016/j.molmet.2018.11.007.

Ducrocq F, Hyde A, Fanet H, Oummadi A, Walle R, De Smedt-Peyrusse V, Layé S, Ferreira G, Trifilieff P, Vancassel S (2019). Decrease in Operant Responding Under Obesogenic Diet Exposure is not Related to Deficits in Incentive or Hedonic Processes. Obesity (Silver Spring). 27(2):255-263. doi: 10.1002/oby.22358.

Rey CDelpech JC, Madore C, Nadjar A, Greenhalgh AD, Amadieu C, Aubert A, Pallet V, Vaysse C, Layé S, Joffre C (2019). Dietary n-3 long chain PUFA supplementation promotes a pro-resolving oxylipin profile in the brain. Brain Behav Immun. 76:17-27. doi: 10.1016/j.bbi.2018.07.025.

Bensalem J, Dudonné S, Etchamendy N, Pellay H, Amadieu C, Gaudout D, Dubreuil S, Paradis ME, Pomerleau S, Capuron L, Hudon C, Layé S, Desjardins Y, Pallet V (2019). Polyphenols From Grape and Blueberry Improve Episodic Memory in Healthy Elderly with Lower Level of Memory Performance: A Bicentric Double-Blind, Randomized, Placebo-Controlled Clinical Study. J Gerontol A Biol Sci Med Sci. 74(7):996-1007. doi: 10.1093/gerona/gly166.



Joffre C, Dinel Anne-Laure, Layé S. Neuro-inflammation dans les maladies neurologiques. Rôle des probiotiques. Phytothérapie 16:326-335.

Berenguer M, Darnaudery M, Claverol S, Bonneu M, Lacombe D, Rooryck C. Prenatal retinoic acid exposure reveals candidate genes for craniofacial disorders. Sci Rep. 8:17492.

Desmoulins L, Chrétien C, Paccoud R, Collins S, Cruciani-Guglielmacci C, Galinier A, Liénard F, Quinault A, Grall S, Allard C, Fenech C, Carneiro L, Mouillot T, Fournel A, Knauf C, Magnan C, Fioramonti X, Pénicaud L, Leloup C. Mitochondrial dynamin-related protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing. Mol Metab (in press).

De Smedt-Peyrusse V, Darriet L, Trifilieff P, Herzog E, Angelo MF. Subcellular fractionation of brain tissue from small tissue explants. Synaptosomes pp75-84. The Neuromethods book series (NM, volume 141).

Tournissac M, Vandal M, Tremblay C, Bourassa P, Vancassel S, Emond V, Gangloff A, Calon F. Dietary intake of branched-chain amino acids in a mouse model of Alzheimer's disease: Effects on survival, behavior, and neuropathology. Alzheimer and Dementia: Translational Research and Clinical Interventions (in press).

Vancassel S, Capuron L, Castanon N. Brain Kynurenine and BH4 Pathways: Relevance to the Pathophysiology and Treatment of Inflammation-Driven Depressive Symptoms. Front Neurosci. 2018 Jul 24;12:499.

Larrieu T, Layé S. Food for mood: Relevance of Nutritional Omega-3 Fatty Acids for Depression and Anxiety. Front Physiol. 9:1047.

Nadjar A. Role of metabolic programming in the modulation of microglia phagocytosis by lipids. Prostaglandins Leukot Essent Fatty Acids. 135:63-73.

Bensalem J, Dudonné S, Etchamendy N, Pellay H, Amadieu C, Gaudout D, Dubreuil S, Paradis ME, Pomerleau S, Capuron L, Hudon C, Layé S, Desjardins Y, Pallet VPolyphenols from grape and blueberry improve episodic memory in healthy elderly with lower level of memory performance: a bicentric double-blind, randomized, placebo-controlled clinical study. J Gerontol A Biol Sci Med Sci. 2018 Jul 19

Bensalem J, Dudonné S, Gaudout D, Servant L, Calon F, Desjardins Y, Layé S, Lafenetre P, Pallet V. Polyphenol-rich extract from grape and blueberry attenuates cognitive decline and improves neuronal function in aged mice. J Nutr Sci. 7:e19.

Labrousse VF, Leyrolle Q, Amadieu C, Aubert A, Sere A, Coutureau E, Grégoire S, Bretillon L, Pallet V, Gressens P, Joffre C, Nadjar A, Layé S. Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory deficits in mice exposed to lipopolysaccharide during gestation. Brain Behav Immun. 2018 Jun 4.

Rey C, Nadjar A, Joffre F, Amadieu C, Aubert A, Vaysse C, Pallet V, Layé S, Joffre C. Maternal n-3 polyunsaturated fatty acid dietary supply modulates microglia lipid content in the offspring. Prostaglandins Leukot Essent Fatty Acids. 133:1-7.

André C, Catania C, Remus-Borel J, Ladeveze E, Leste-Lasserre T, Mazier W, Binder E, Gonzales D, Clark S, Guzman-Quevedo O, Abrous DN, Layé S, Cota D. mTORC1 pathway disruption abrogates the effects of the ciliary neurotrophic factor on energy balance and hypothalamic neuroinflammation. Brain Behav Immun. 70:325-334.

Delgado I, Huet L, Dexpert S, Beau C, Forestier D, Ledaguenel P, Aubert A, Sauvant J, Aouizerate B, Magne E, Capuron L. Depressive symptoms in obesity: Relative contribution of low-grade inflammation and metabolic health. Psychoneuroendocrinology. 91:55-61.

Gueye AB, Vendruscolo LF, de Ávila C, Le Moine C, Darnaudéry M, Cador M. Unlimited sucrose consumption during adolescence generates a depressive-like phenotype in adulthood. Neuropsychopharmacology. 2018 Feb 27.

Miquel S, Champ C, Day J, Aarts E, Bahr BA, Bakker M, Bánáti D, Calabrese V, Cederholm T, Cryan J, Dye L, Farrimond JA, Korosi A, Layé S, Maudsley S, Milenkovic D, Mohajeri MH, Sijben J, Solomon A, Spencer JPE, Thuret S, Vanden Berghe W, Vauzour D, Vellas B, Wesnes K, Willatts P, Wittenberg R, Geurts L. Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions. Ageing Res Rev. 42:40-55.

Rincel M, Lépinay AL, Janthakhin Y, Soudain G, Yvon S, Da Silva S, Joffre C, Aubert A, Séré A, Layé S, Theodorou V, Ferreira G, Darnaudéry M. Maternal high-fat diet and early life stress differentially modulate spine density and dendritic morphology in the medial prefrontal cortex of juvenile and adult rats. Brain Struct Funct 223:883-895.

Naneix F, Darlot F, De Smedt-Peyrusse V, Pape JR, Coutureau E, Cador M (2018). Protracted motivational dopamine-related deficits following adolescence sugar overconsumption. Neuropharmacology 129:16-25.

Layé S, Nadjar N., Joffre C., Bazinet RP (2018). Anti-inflammatory effects of omega-3 fatty acids in the brain: physiological mechanisms and relevance to pharmacology. Pharm Rev 70:12-38.


Naneix F, Tantot F, Glangetas C, Kaufling J, Janthakhin Y, Boitard C, De Smedt-Peyrusse V, Pape JR, Vancassel S, Trifilieff P, Georges F, Coutureau E, Ferreira G. (2017). Impact of Early Consumption of High-Fat Diet on the Mesolimbic Dopaminergic System. eNeuro. 2017 Jun 1;4(3).

Trifilieff P, Ducrocq F, van der Veldt S, Martinez D. (2017). Blunted Dopamine Transmission in Addiction: Potential Mechanisms and Implications for Behavior. Semin Nucl Med. 47:64-74.

Calder PC, Bosco N, Bourdet-Sicard R, Capuron L, Delzenne N, Doré J, Franceschi C, Lehtinen MJ, Recker T, Salvioli S, Visioli F. (2017). Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition. Ageing Res Rev. 40:95-119.

Lagarrigue A, Ajana S, Capuron L, Féart C, Moisan MP. (2017). Obesity in French Inmates: Gender Differences and Relationship with Mood, Eating Behavior and Physical Activity. PLoS One. 12:e0170413.

Capuron L, Lasselin J, Castanon N. (2017). Role of Adiposity-Driven Inflammation in Depressive Morbidity. Neuropsychopharmacology. 42:115-128.

Capuron L, Castanon N. (2017). Role of Inflammation in the Development of Neuropsychiatric Symptom Domains: Evidence and Mechanisms. Curr Top Behav Neurosci. 31:31-44.

Chianese R, Coccurello R, Viggiano A, Scafuro M, Fiore M, Coppola G, Operto FF, Fasano S, Layé S, Pierantoni R, Meccariello R. (2017). Impact of dietary fats on brain functions. Curr Neuropharmacol. 2017 Oct 17. 

Rincel M, Lépinay AL, Janthakhin Y, Soudain G, Yvon S, Da Silva S, Joffre C, Aubert A, Séré A, Layé S, Theodorou V, Ferreira G, Darnaudéry M. (2017). Maternal high-fat diet and early life stress differentially modulate spine density and dendritic morphology in the medial prefrontal cortex of juvenile and adult rats. Brain Struct Funct. Oct 11.

Fourrier C, Remus-Borel J, Greenhalgh AD, Guichardant M, Bernoud-Hubac N, Lagarde M, Joffre C, Layé S. (2017). Docosahexaenoic acid-containing choline phospholipid modulates LPS-induced neuroinflammation in vivo and in microglia in vitro. J Neuroinflammation. 14:170.

Manduca A, Bara A, Larrieu T, Lassalle O, Joffre C, Layé S, Manzoni OJ. (2017). Amplification of mGlu5-Endocannabinoid Signaling Rescues Behavioral and Synaptic Deficits in a Mouse Model of Adolescent and Adult Dietary Polyunsaturated Fatty Acid Imbalance. J Neurosci. 37:6851-6868.

de Cossío LF,Fourrier C, Sauvant J, Everard A, Capuron L, Cani PD, Layé S, Castanon N. (2017). Impact of prebiotics on metabolic and behavioral alterations in a mouse model of metabolic syndrome. Brain Behav Immun. 64:33-49.

André C, Guzman-Quevedo O, Rey C, Rémus-Borel J, Clark S, Castellanos-Jankiewicz A, Ladeveze E, Leste-Lasserre T, Nadjar A, Abrous DN, Laye S, Cota D. (2017). Inhibiting Microglia Expansion Prevents Diet-Induced Hypothalamic and Peripheral Inflammation. Diabetes. 2017 66:908-919. 

Nadjar A, Leyrolle Q, Joffre C, Laye S. (2017). Bioactive lipids as new class of microglial modulators: when nutrition meets neuroimmunology. Prog Neuropsychopharmacol Biol Psychiatry. 2017 79:19-26.

Thomazeau A, Bosch-Bouju C, Manzoni O, Layé S (2017). Nutritional n-3 PUFA Deficiency Abolishes Endocannabinoid Gating of Hippocampal Long-Term Potentiation. Cereb Cortex 27:2571-2579. 

Romaní-Pérez M, Lépinay AL, Alonso L, Rincel M, Xia L, Fanet H, Caillé S, Cador M, Layé S, Vancassel S, Darnaudéry M. (2017). Impact of perinatal exposure to high-fat diet and stress on responses to nutritional challenges, food-motivated behaviour and mesolimbic dopamine function. Int J Obes (Lond) 41:502-509.


Fernández de Cossío L, Fourrier C, Sauvant J,Everard A, Capuron L, Cani PD, Layé S, Castanon N. Impact of prebiotics on metabolic and behavioral alterations in a mouse model of metabolic syndrome. Brain Behav Immun. 2017 (In press)

Moisan MP and Castanon N. Emerging Role of Corticosteroid-Binding Globulin in Glucocorticoid-Driven Metabolic Disorders. Frontiers in Endocrinology (In press)

Romaní-Pérez M, Lépinay AL, Alonso L, Rincel M, Xia L, Fanet H, Caillé S, Cador M, Layé S, Vancassel S, Darnaudéry M. Impact of perinatal exposure to high-fat diet and stress on responses to nutritional challenges, food-motivated behaviour and mesolimbic dopamine function. Int J Obes (Lond). 2016 Dec 27.

André C, Guzman-Quevedo O, Rey C, Rémus-Borel J, Clark S, Castellanos-Jankiewicz A, Ladeveze E, Leste-Lasserre T, Nadjar A, Abrous DN, Layé S, Cota D (2016). Inhibiting microglial expansion prevents diet-induced hypothalamic and peripheral inflammation. Diabetes Nov 30. pii: db160586.

Rincel M, Lepinay AL, Delage P, Fioramonti J, Theodorou VS, Laye S, Darnaudery M (2016). Maternal high-fat diet prevents developmental programming by early-life stress. Transl Psychiatry 6, e966.

Joffre C, Dinel AL, Aubert A, Fressange-Mazda C, Le Ruyet P, Layé S (2016). Impact of Lactobacillus fermentum and dairy lipids in the maternal diet on the fatty acid composition of pups’ brain and peripheral tissues. Prostaglandins Leukot Essent Fatty Acids. 115:24-34.

Joffre C, Grégoire S, De Smedt V, Acar N, Bretillon L, Nadjar, A, Layé S (2016). Modulation of brain PUFA in different experimental models of mice. Prostaglandins Leukot Essent Fatty Acids. 114:1-10.

Dinel AL, Rey C, Baudry C, Fressange-Mazda C, Le Ruyet P, Nadjar A, Pallet P, Joffre C, Layé S (2016). Enriched dairy fat matrix diet prevents early life lipopolysaccharide-induced spatial memory impairment at adulthood. Prostaglandins Leukot Essent Fatty Acids. 2016 Oct;113:9-18.

Bosch-Bouju C, Larrieu T, Linders L, Manzoni OJ, Layé S. (2016). Endocannabinoid-Mediated Plasticity in Nucleus Accumbens Controls Vulnerability to Anxiety after Social Defeat Stress. Cell Rep. 16:1237-42.

Capuron L, Lasselin J, Castanon N. (2016). Role of Adiposity-Driven Inflammation in Depressive Morbidity. Neuropsychopharmacology, in press.

Nadjar A, Leyrolle Q, Joffre C, Laye S. (2016). Bioactive lipids as new class of microglial modulators: When nutrition meets neuroimunology. Prog Neuropsychopharmacol Biol Psychiatry, in press.

Delpierre,C., Barbosa--‐Solis,C., Torrisani,J., Darnaudéry,M., Bartley,M., Blane,D., Kelly-Irving,M., Getz,L. & Tomasdottir,M.O., Roberston,T. & Gustafsson,P. (2016).Origins of health inequalities:the case for Allostatic Load.Longitudinal and Life Course Studies,7,79–103.

Capuron L, Castanon N. (2016) Role of Inflammation in the Development of Neuropsychiatric Symptom Domains: Evidence and Mechanisms. Curr Top Behav Neurosci. 2016 May 25.

Dinel AL, Rey C, Bonhomme C, Le Ruyet P, Joffre C, Layé S. (2016) Dairy fat blend improves brain DHA and neuroplasticity and regulates corticosterone in mice. Prostaglandins Leukot Essent Fatty Acids. 2016 Jun;109:29-38.

Abiega O, Beccari S, Diaz-Aparicio I, Nadjar A, Layé S, Leyrolle Q, Gómez-Nicola D, Domercq M, Pérez-Samartín A, Sánchez-Zafra V, Paris I, Valero J, Savage JC, Hui CW, Tremblay MÈ, Deudero JJ, Brewster AL, Anderson AE, Zaldumbide L, Galbarriatu L, Marinas A, Vivanco Md, Matute C, Maletic-Savatic M, Encinas JM, Sierra A. (2016) Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling. PLoS Biol. 2016 May 26;14(5):e1002466.

Lasselin J, Magne E, Beau C, Aubert A, Dexpert S, Carrez J, Layé S, Forestier D, Ledaguenel P, Capuron L. (2016) Low-grade inflammation is a major contributor of impaired attentional set shifting in obese subjects. Brain Behav Immun. 2016 May 17.

Thomazeau A, Bosch-Bouju C, Manzoni O, Layé S. (2016) Nutritional n-3 PUFA Deficiency Abolishes Endocannabinoid Gating of Hippocampal Long-Term Potentiation.Cereb Cortex. 2016 Mar 5.

Hamer M, Dye L, Siobhan Mitchell E, Layé S, Saunders C, Boyle N, Schuermans J, Sijben (2016) Examining techniques for measuring the effects of nutrients on mental performance and mood state.J. Eur J Nutr. 2016 Jan 7.

Rey C, Nadjar A, Buaud B, Vaysse C, Aubert A, Pallet V, Layé S, Joffre C (2016). Resolvin D1 and E1 promote resolution of inflammation in microglial cells in vitro.Brain Behav Immun. 2015 Dec 21. S0889-1591(15)30075-1.

Larrieu T, Hilal ML, De Smedt-Peyrusse V, Sans N, Layé S (2016). Nutritionnal omega-3 deficiency alters glucocorticoid receptor-signaling pathway and neuronal morphology in regionally distinct brain structures associated with emotional deficits. Neural Plasticity.


  1. Awad W, Ferreira G* & Maroun M* (2015). Dissociation of the role of infralimbic cortex in learning and consolidation of extinction of recent and remote aversion memory. Neuropsychopharmacology, 40(11): 2566-2575. *equal contribution
  2. Schneider N, Datiche F, Wilson DA, Gigot V, Thomas-Danguin T, Ferreira G & Coureaud G (2015). Brain processing of a configural versus elemental odour mixture in the newborn rabbit. Brain, Structure & Function, in press.
  3. Guillemin I, Marrel A, Arnould B, Capuron L, Dupuy A, Ginon E, Layé S, Lecerf JM, Prost M, Rogeaux M, Urdapilleta I, Allaert FA. How French subjects describe well-being from food and eating habits? Development, item reduction and scoring definition of the Well-Being related to Food Questionnaire (Well-BFQ©). Appetite. 2015; 96:333-346.
  4. Vauzour D, Martinsen A, Layé S. Neuroinflammatory processes in cognitive disorders: Is there a role for flavonoids and n-3 polyunsaturated fatty acids in counteracting their detrimental effects? Neurochem Int. 2015 89:63-74.
  5. Castanon N, Luheshi G, Layé S. Role of neuroinflammation in the emotional and cognitive alterations displayed by animal models of obesity. Front Neurosci. 2015 9:229.
  6. Delpech JC, Thomazeau A, Madore C, Bosch-Bouju C, Larrieu T, Lacabanne C, Remus-Borel J, Aubert A, Joffre C, Nadjar A, Layé S.Dietary n-3 PUFAs Deficiency Increases Vulnerability to Inflammation-Induced Spatial Memory Impairment. Neuropsychopharmacology. 2015; 40(12):2774-87.
  7. Boitard C, Maroun M, Tantot F, Cavaroc A, Sauvant J, Marchand A, Layé S, Capuron L, Darnaudery M, Castanon N, Coutureau E, Vouimba RM, Ferreira G. Juvenile obesity enhances emotional memory and amygdala plasticity through glucocorticoids.. J Neurosci. 2015;35(9):4092-103.
  8. Lépinay AL, Larrieu T, Joffre C, Acar N, Gárate I, Castanon N, Ferreira G, Langelier B, Guesnet P, Brétillon L, Parnet P, Layé S, Darnaudéry M. Perinatal high-fat diet increases hippocampal vulnerability to the adverse effects of subsequent high-fat feeding..Psychoneuroendocrinology. 2015 ;53:82-93. doi: 10.1016/j.psyneuen.2014.12.008. Epub 2014 Dec 15.
  9. Delpech JC, Saucisse N, Aubert A, Casenave F, Sans N, Layé S, Ferreira G* & Nadjar A* (2015). Microglial activation enhances associative taste memory through purinergic modulation of glutamatergic neurotransmission. J Neurosci. 2015 Feb 18;35(7):3022-33. *equal contribution
  10. Delpech JC, Madore C, Nadjar A, Joffre C, Wohleb ES, Layé S.Microglia in neuronal plasticity: Influence of stress. Neuropharmacology. 2015 Sep;96(Pt A):19-28. doi: 10.1016/j.neuropharm.2014.12.034. Epub 2015 Jan 9. Review.
  11. Delpech JC, Madore C, Joffre C, Aubert A, Kang JX, Nadjar A, Layé S. Transgenic increase in n-3/n-6 fatty acid ratio protects against cognitive deficits induced by an immune challenge through decrease of neuroinflammation. Neuropsychopharmacology. 2015 40(3):525-36.
  12. Lafitte M, Tastet S, Perez P, Serisé MA, Grandoulier AS, Aouizerate B, Sibon I, Capuron L, Couffinhal T. High sensitivity C reactive protein, fibrinogen levels and the onset of major depressive disorder in post-acute coronary syndrome. BMC Cardiovasc Disord. 2015 15:23.
  13. Fioriti L., Myers C., Huang YY., Li X., Stephan J., Trifilieff P., Conalghi L., Kosmidis S., Drisaldi B., Pavlopoulos E. and Kandel ER. The persistence of memory in the hippocampus requires protein synthesis mediated by the prion-like protein CPEB3. Neuron, 2015; 86(6):1433-48. PMID: 26074003
  14. Frederick AL.*, Yano H.*, Trifilieff P.*, Vishwasrao HD., Biezonski D., Meszaros J., Sibely DR., Kellendonk K., Sonntag K., Graham DL, Colbran RJ., Stanwood GD. and Javitch JA. Evidence against dopamine D1/D2 receptor heteromers. Molecular Psychiatry, 2015; 20(11):1373-85. *equally contributed. PMID: 25560761.    
  15. Biezonski DK., Trifilieff P., Meszaros J., Javitch JA. and Kellendonk C. Evidence for limited D1 and D2 receptor co-expression and co-localization within the striatum of the neonatal mouse. The Journal of Comparative Neurology, 2015; 523(8):1175-89. PMID: 25556545.
  16. Lafitte M, Tastet S, Perez P, Serisé MA, Grandoulier AS, Aouizerate B, Sibon I, Capuron L, Couffinhal T.High sensitivity C reactive protein, fibrinogen levels and the onset of major depressive disorder in post-acute coronary syndrome.BMC Cardiovasc Disord. 2015 Mar 18;15:23. doi: 10.1186/s12872-015-0015-3
  17. Barboza Solís C, Kelly-Irving M, Fantin R, Darnaudéry M, Torrisani J, Lang T, Delpierre C. Adverse childhood experiences and physiological wear-and-tear in midlife: Findings from the 1958 British birth cohort. Proc Natl Acad Sci U S A. 2015 ; 112(7):E738-4.
  18.  Soria-Gomez E, Busquets-Garcia A., Hu F., Mehidi A., Cannich A., Roux L., Louit I.,  Alonso L., Wiesner T., Georges F;, Verrier D., Vincent P., Ferreira G., Luo M. and Marsicano G. Habenular CB1 Receptors Control the Expression of Aversive Memories, Neuron 2015;88(2):306-13.
  1. Parkes S, De la Cruz V, Bermudez-Rattoni F, Coutureau E & Ferreira G (2014). Differential role of insular cortex muscarinic and NMDA receptors in one-trial appetitive taste learning. Neurobiology of Learning and Memory, 116: 112-116.
  2. Hegoburu C, Parrot S, Ferreira G & Mouly AM (2014). Differential involvement of amygdala and cortical NMDA receptors activation upon encoding in odor fear memory. Learning & Memory, 21(12):651-5.
  3. Lépinay AL, Larrieu T, Joffre C, Acar N, Gárate I, Castanon N, Ferreira G, Langelier B, Guesnet P, Brétillon L, Parnet P, Layé S, Darnaudéry M.Perinatal high-fat diet increases hippocampal vulnerability to the adverse effects of subsequent high-fat feeding.Psychoneuroendocrinology. 2014 Dec 15;53C:82-93
  4. Richard P. Bazinet and Sophie Layé. Polyunsaturated fatty acids and their metabolites in brain function and disease, Nat Rev Neurosci. 2014 Nov 12
  5. Pietropaolo S, Goubran MG, Joffre C, Aubert A, Lemaire-Mayo V, Crusio WE, Layé S.Dietary supplementation of omega-3 fatty acids rescues fragile X phenotypes in Fmr1-Ko mice.Psychoneuroendocrinology.2014 Nov;49:119-29
  6. Létondor A, Buaud B, Vaysse C, Fonseca L, Herrouin C, Servat B, Layé S, Pallet V, Alfos S.Erythrocyte DHA level as a biomarker of DHA status in specific brain regions of n-3 long-chain PUFA-supplemented aged rats.Br J Nutr. 2014 Oct 21:1-14.
  7. Udina, M., Hidalgo, D., Navines, R., Forns, X., Solà, R., Farré, M. Capuron, L., Vieta, E. Martin-Santos, R.Prophylactic antidepressant treatment of interferon-induced depression in chronic hepatitis C: a systematic review and meta-analysis. Journal of Clinical Psychiatry.2014 Oct;75(10):e1113-21
  8. Larrieu T, Hilal LM, Fourrier C, De Smedt-Peyrusse V, Sans N, Capuron L, Layé S.Nutritional omega-3 modulates neuronal morphology in the prefrontal cortex along with depression-related behaviour through corticosterone secretion.Transl Psychiatry. 2014 Sep 9;4:e437
  9. Delpech JC, Madore C, Joffre C, Aubert A, Kang JX, Nadjar ALayé STransgenic Increase in n-3/n-6 Fatty Acid Ratio Protects Against Cognitive Deficits Induced by an Immune Challenge through Decrease of Neuroinflammation.Neuropsychopharmacology. 2014 Aug 5
  10. Udina, M., Moreno-Espana, J., Capuron, L., Farré, M., Vieta, E., Matin-Santos., R. Cytokine-induced depression: current status and novel targets for depression therapy. CNS Neurological Disorders -Drug Targets  2014;13(6):1066-74.
  11. Boitard C, Cavaroc A, Sauvant J, Aubert A, Castanon N, Layé S, Ferreira G. Impairment of hippocampal-dependent memory induced by juvenile high-fat diet intake is associated with enhanced hippocampal inflammation in rats. Brain, Behav, Immun 2014 Aug;40:9-17.
  12. Coureaud G, Thomas-Danguin T, Wilson DA, Ferreira G. Neonatal representation of odour objects: distinct memories of the whole and its parts Proc Biol Sci. 2014 Aug 22;281(1789). 
  13. Coureaud G, Thomas-Danguin T, Datiche F, Wilson DA, Ferreira G. Differential memory persistence of odor mixture and components in newborn rabbits: competition between the whole and its parts. Front Behav Neurosci. 2014 Jun 16;8:211
  14. Castanon N, Lasselin J, Capuron LNeuropsychiatric comorbidity in obesity: role of inflammatory processes. Front Endocrinol (Lausanne). 2014 May 15;5:74. Review
  15. Madore C, Nadjar A, Delpech JC, Sere A, Aubert A, Portal C1, Joffre C, Layé S.Nutritional n-3 PUFAs deficiency during perinatal periods alters brain innate immune system and neuronal plasticity-associated genes. Brain Behav Immun. 2014 Apr 13.
  16. Capuron L, Geisler S, Kurz K, Leblhuber F, Sperner-Unterweger B, Fuchs D. Activated Immune System and Inflammation in Healthy Ageing: Relevance for Tryptophan and Neopterin Metabolism. Curr Pharm Des. 2014 Mar 17.
  17. André C, Dinel AL, Ferreira G, Layé S, Castanon NDiet-induced obesity progressively alters cognition, anxiety-like behavior and lipopolysaccharide-induced depressive-like behavior: Focus on brain indoleamine 2,3-dioxygenase activation. Brain Behav Immun. 2014, 41, 10-21.
  18. Lasselin J, Capuron L. Chronic low-grade inflammation in metabolic disorders: relevance for behavioral symptoms. Neuroimmunomodulation. 2014;21(2-3):95-101.
  19. Soria-Gómez E, Bellocchio L, Reguero L, Lepousez G, Martin C, Bendahmane M, Ruehle S, Remmers F, Desprez T, Matias I, Wiesner T, Cannich A, Nissant A, Wadleigh A, Pape HC, Chiarlone AP, Quarta C, Verrier D, Vincent P, Massa F, Lutz B, Guzmán M, Gurden H, Ferreira G, Lledo PM, Grandes P, Marsicano G. The endocannabinoid system controls food intake via olfactory processes. Nat Neurosci. 2014 Feb 9. doi: 10.1038/nn.3647. [Epub ahead of print] (en savoir plus)
  20. Sauvant J, Delpech JC, Palin K, De Mota N, Dudit J, Aubert A, Orcel H, Roux P, Layé S, Moos F, Llorens-Cortes C, Nadjar AMechanisms involved in dual vasopressin/apelin neuron dysfunction during aging. PLoS One. 2014 Feb 5;9(2):
  21. Dinel AL, André CAubert AFerreira GLayé S,Castanon NLipopolysaccharide-induced brain activation of the indoleamine 2,3-dioxygenase and depressive-like behavior are impaired in a mouse model of metabolic syndrome. Psychoneuroendocrinology Volume 40, February 2014, Pages 48–59
  22. Trifilieff P, Martinez D.Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity. Neuropharmacology. 2014 Jan;76Pt B:498-509.
  23. Lasselin J, Magne E, Beau C, Ledaguenel P, Dexpert S, Aubert A, Layé S, Capuron L. Adipose inflammation in obesity: relationship with circulating levels of inflammatory markers and association with surgery-induced weight loss. J Clin Endocrinol Metab. 2014 Jan;99(1):E53-61.
  24. Dantzer R, Heijnen CJ, Kavelaars A, Laye SCapuron L.The neuroimmune basis of fatigue.Trends Neurosci.2014 Jan;37(1):39-46.

  1. Palesh O, Aldridge-Gerry A, Ulusakarya A, Ortiz-Tudela E, Capuron L, Innominato PF.  Sleep disruption in breast cancer patients and survivors.  J Natl Compr Canc Netw. 2013 Dec 1;11(12):1523-30
  2. Dantzer R, Heijnen CJ, Kavelaars A, Laye SCapuron L.The neuroimmune basis of fatigue.Trends Neurosci.2013 Nov 12. pii: S0166-2236(13) 00196-3. doi: 10.1016/j.tins.2013.10.003. [Epub ahead of print]
  3. Binder E, Bermúdez-Silva FJ, André C, Elie M, Romero-Zerbo SY, Leste-Lasserre T, Belluomo L, Duchampt A, Clark S, Aubert A, Mezzullo M, Fanelli F, Pagotto U, Layé S, Mithieux G, Cota D. Leucine Supplementation Protects from Insulin Resistance by Regulating Adiposity Levels.  PLoS One. 2013 Sep 25;8(9):e74705.
  4. Coureaud G,Tourat A and Ferreira G. Sensory preconditioning in newborn rabbits: from common to distinct odor memories.Learning Memory sept. 2013 20 (9)
  5. Udina M, Moreno-España J, Navinés R, Giménez D, Langohr K, Gratacòs M, Capuron L, de la Torre R, Solà R, Martín-Santos R. Serotonin and interleukin-6: the role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms.Psychoneuroendocrinology. 2013 Sep;38(9):1803-13. doi: 10.1016/j.psyneuen.2013.03.007. Epub 2013 Apr 6.
  6. Trifilieff P, Feng B, Urizar E, Winiger V, Ward RD, Taylor KM, Martinez D, Moore H, Balsam PD, Simpson EH, Javitch JA. Increasing dopamine D2 receptor expression in the adult nucleus accumbens enhances motivation. Mol Psychiatry. 2013 Sep;18(9):1025-33. doi: 10.1038/mp.2013.57. Epub 2013 May 28
  7. Udina M, Navinés R, Capuron L, Martín-Santos R. A response to the commentary "Indolamine 2,3-dioxygenase regulation and neuropsychiatric symptoms" by Loftis, J.M. on "Serotonin and interleukin-6: the role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms" by Udina, M., Moreno-España, J., Navinés, R., Gimenez, D., Langohr, K., Gratacòs, M., Capuron, L., de la Torre, R., Solà, R., Martin-Santos, R. http:\\ 2013 Sep;38(9):1830-1. doi: 10.1016/j.psyneuen.2013.05.019. Epub 2013 Jun 28. No abstract available
  8. Udina M, Moreno-España J, Navinés R, Giménez D, Langohr K, Gratacòs M, Capuron L, de la Torre R, Solà R, Martín-Santos R. Serotonin and interleukin-6: the role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms.Psychoneuroendocrinology. 2013 Sep;38(9):1803-13. doi: 10.1016/j.psyneuen.2013.03.007. Epub 2013 Apr 6.
  9. Madore CJoffre CDelpech JCDe Smedt-Peyrusse VAubert A, Coste L, Layé SNadjar AEarly morphofunctional plasticity of microglia in response to acute lipopolysaccharide.  Brain Behav Immun. 2013 Aug 28. pii: S0889-1591(13)00419-4. doi: 10.1016/j.bbi.2013.08.008. [Epub ahead of print] (en savoir plus...)
  10. Trifilieff P, Martinez D. Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity. Neuropharmacology. 2013 Jul 10.pii: S0028-3908(13)00300-6.
  11. Trifilieff P, Martinez D. Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence.Front Psychiatry. 2013 Jun 3;4:44.
  12. Nadjar A, Blutstein T, Aubert A, Laye S, Haydon PG. Astrocyte-derived adenosine modulates increased sleep pressure during inflammatory response.Glia.2013 May;61(5):724-31. doi: 10.1002/glia.22465. Epub 2013 Feb 4.
  13. Layé S. What do you eat? Dietary omega 3 can help to slow the aging process.Brain Behav Immun. 2013 Feb;28:14-5. doi: 10.1016/j.bbi.2012.11.002. Epub 2012 Nov 10. No abstract available
  14. Julia C, Ciangura C, Capuron L, Bouillot JL, Basdevant A, Poitou C, Oppert JM. Quality of life after Roux-en-Y gastric bypass and changes in body mass index and obesity-related comorbidities. Diabetes Metab. 2013Jan9. doi:pii: S1262-3636(12)00215-7. 10.1016/j.diabet.2012.10.008.

  1. Larrieu T, Madore C, Joffre C, Layé S.Nutritional n-3 polyunsaturated fatty acids deficiency alters cannabinoid receptor signaling pathway in the brain and associated anxiety-like behavior in mice.J Physiol Biochem. 2012 Dec;68(4):671-81. doi: 10.1007/s13105-012-0179-6. Epub 2012 Jun 16
  2. Schaefer M, Capuron L, Friebe A, Diez-Quevedo C, Robaeys G, Neri S, Foster GR, Kautz A, Forton D, Pariante CM. Hepatitis C infection, antiviral treatment and mental health: a European expert consensus statement. J Hepatol. 2012 Dec;57(6):1379-90. doi: 10.1016/j.jhep.2012.07.037. Epub 2012 Aug 7.
  3. Labrousse VF, Nadjar A,Joffre C, Costes L, Aubert A, Grégoire S , Bretillon L ,  Layé S. Short-Term Long Chain Omega3 Diet Protects from Neuroinflammatory Processes and Memory Impairment in Aged Mice.PLoS ONE  2012 7(5): e36861(IF4.41)
  4.  Dejean C, Nadjar A, Le Moine C, Bioulac B, Gross CE, Boraud T. Evolution ofthe dynamic properties of the cortex-basal ganglia network after dopaminergicdepletion in rats.Neurobiol Dis. 2012May;46(2):402-13. Epub 2012 Feb 12. PubMed PMID: 22353564.
  5. Boitard C, Etchamendy N, Sauvant J, Aubert A, Tronel S, Marighetto A, Layé S, Ferreira G. Juvenile, but not adult, exposure to high-fat diet impairs relational memory and hippocampal neurogenesis in mice.Hippocampus2012, 22:2095-2100 (IF5.176)
  6. Laloux C, Mairesse J, Van Camp G, Giovine A, Branchi I, Bouret S, Morley-Fletcher S, Bergonzelli G, Malagodi M, Gradini R, Nicoletti F, Darnaudéry M*, Maccari S*. Anxiety-like behaviour and associated neurochemical and endocrinological alterations in male pups exposed to prenatal stress.Psychoneuroendocrinology. 2012Oct;37(10):1646-58 (IF5.264)   *contibuted equally
  7. Lasselin J, Layé S, Barreau JB, Rivet A, Dulucq MJ, Gin H, Capuron L.Fatigue and cognitive symptoms in patients with diabetes: Relationship with disease phenotype and insulin treatment. Psychoneuroendocrinology.2012;37(9):1468-78 (IF5.264)
  8. Lasselin J, Layé S, Dexpert S, Aubert A, Gonzalez C, Gin H, Capuron L.Fatigue Symptoms Relate to Systemic Inflammation in Patients with Type 2 Diabetes" .Brain Behavior and Immunity, 2012;26(8):1211-9 (IF4.946)
  9. Moranis A, Delpech JC, De Smedt-Peyrusse V, Aubert A, Guesnet P, Lavialle M, Joffre C, Layé S. Long term adequate n-3 polyunsaturated fatty acid diet protects from depressive-like behavior but not from working memory disruption and brain cytokine expression in aged mice.Brain Behav Immun. 2012Jul;26(5):721-31 (IF4.946)
  10. Lévy F. & Ferreira G. (2012). Les apprentissages alimentaires et sociaux régulés par l’olfaction : mécanismes comportementaux et neurobiologiques. pp 323-338. In : Odorat et goût : De la neurobiologie des sens chimiques aux applications (coodinateurs : Roland Salesse et Rémi Gervais; éditions Quae, Versailles, 2012, 539 pages).

  1. Dinel AL, André C, Aubert A, Ferreira G, Layé S, Castanon N.Cognitive and emotional alterations are related to hippocampal inflammation in a mouse model of metabolic syndrome.PLoS One.2011;6(9):e24325. Epub2011 Sep 16 (IF4.351)
  2. Van Waes V, Darnaudéry M, Marrocco J, Gruber SH, Talavera E, Mairesse J, Van Camp G, Casolla B, Nicoletti F, Mathé AA, Maccari S, Morley-Fletcher S. Impact of early life stress on alcohol consumption and on the short- and long-term responses to alcohol in adolescent female rats.Behav Brain Res. 2011 Aug 1;221(1):43-9.
  3. Castro-Alvarez JF, Gutierrez-Vargas J, Darnaudéry M, Cardona-Gómez GP. ROCK inhibition prevents tau hyperphosphorylation and p25/CDK5 increase after global cerebral ischemia.Behav Neurosci.2011 Jun;125(3):465-72. 
  4. Capuron L, Miller AH. Immune System to Brain Signaling: Neuropsychopharmacological Implications.Pharmacol Therapeut2011 May; 130(2):226-38 (IF8.897).
  5. Van Waes V, Enache M, Berton O, Vinner E, Lhermitte M, Maccari S, Darnaudéry M. Effect of prenatal stress on alcohol preference and sensitivity to chronic alcohol exposure in male rats.Psychopharmacology (Berl).2011 Mar;214(1):197-208.
  6. Lafourcade M, Larrieu T, Mato S, Duffaud A, Sepers M, Matias I, De Smedt-Peyrusse V, Labrousse VF, Bretillon L, Matute C, Rodríguez-Puertas R, Layé S, Manzoni OJ. Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions.Nat Neurosci (IF14.164).
  7. Capuron L, Schroecksnadel S, Féart C, Aubert A, Higueret D, Barberger-Gateau P, Layé S, Fuchs D. Chronic Low-Grade Inflammation in Elderly Persons Is Associated with Altered Tryptophan and Tyrosine Metabolism: Role in Neuropsychiatric Symptoms.Biol Psychiatry (IF8.672).
  8. Viau S, Leclère L, Buteau B, Grégoire S, Acar N, Bron A, Creuzot-Garcher CP, Bretillon L, Joffre C. Polyunsaturated fatty acids induce modification in the lipid composition and the prostaglandin production of the conjunctival epithelium cells.Graefes Arch Clin Exp Ophthalmol.2011 Sep 6. [Epub ahead of print] PubMed PMID: 21894532.

  1. Destaillats F, Joffre C, Acar N, Joffre F, Bezelgues JB, Pasquis B, Cruz-Hernandez C, Rezzi S, Montoliu I, Dionisi F, Bretillon L. Differential effect of maternal diet supplementation with alpha-Linolenic adcid or n-3 long-chain polyunsaturated fatty acids on glial cell phosphatidylethanolamine and phosphatidylserine fatty acid profile in neonate rat brains. Nutr Metab. 7:2 (IF 3.000).
  2. Gautron L., Laye S. Neurobiology of inflammation-associated anorexia . Frontiers in Neuropharmacology. Volume 1 : 10 p. (Article 3) (IF ?).
  3. Moreau M.L., Sauvant J., Moos F., Palin K. Brain insulin growth factor-I induces diuresis increase through the inhibition of arginin-vasopressin release in aged rats. Neurobiology of aging 31(3):. 532-536, (IF 5.959).
  4. Laye S. Polyunsaturated fatty acids, neuroinflammation and well being. Prostaglandins, leukotrienes and essential fatty acids (82), n°4-6 (187 p.):295-303, (IF 1.366).
  5. Vendruscolo LF, Gueye AB, Vendruscolo JC, Clemens KJ, Mormède P, Darnaudéry M, Cador M. Reduced alcohol drinking in adult rats exposed to sucrose during adolescence. Neuropharmacology 59(6): 388-394, (IF 3.383).
  6. Poindron P., Otal J., Ferreira G., Keller M., Guesdon V., Nowak R., Lévy F. Amniotic fluid is important for the maintenance of maternal responsiveness and the establishment of maternal selectivity in sheep. Animal 4(12): 2057-2064, (IF 0.994).
  7. Capuron L, Poitou C, Machaux-Tholliez D, Frochot V, Bouillot L, Basdevant A, Laye S, Clément K. Relationship between adiposity, emotional status and eating behaviour in obese women: role of inflammation. Psychol Med, (IF 5.012).
  8. Desgranges B, Ramirez-Amaya V, Ricaño-Cornejo I, Lévy F, Ferreira G. Flavor Preference Learning Increases Olfactory and Gustatory Convergence onto Single Neurons in the Basolateral Amygdala but Not in the Insular Cortex in Rats. PLoS One 5(4):e10097, (IF 4.351).
  9. Majer M, Nater UM, Lin JM, Capuron L, Reeves WC. Association of childhood trauma with cognitive function in healthy adults: a pilot study. BMC Neurol 10:61, (IF 2.109).
  10. Vendruscolo LF, Gueye AB, Darnaudéry M, Ahmed SH, Cador M. Sugar overconsumption during adolescence selectively alters motivation and reward function in adult rats. PLoS One 5(2):e9296, (IF 4.351).
  11. Nadjar A, Sauvant J, Combe C, Parnet P, Konsman JP. Brain cyclooxygenase-2 mediates interleukin-1-induced cellular activation in preoptic and arcuate hypothalamus, but not sickness symptoms. Neurobiology of Disease 39(3): 393-401, (IF 4.852).
  12. Van Waes V, Enache M, Berton O, Vinner E, Lhermitte M, Maccari S, Darnaudéry M. Effect of prenatal stress on alcohol preference and sensitivity to chronic alcohol exposure in male rats. Psychopharmacology, (IF 3.676).
  13. Viau S, Pasquis B, Maire MA, Fourgeux C, Grégoire S, Acar N, Bretillon L, Creuzot-Garcher CP, Joffre C. No consequences of dietary n-3 polyunsaturated fatty acid deficiency on the severity of scopolamine-induced dry eye. Graefes Arch Clin Exp Ophthalmol, (IF 1.77).
  14. Lévy F., Keller M., Cornilleau F, Moussu F., Ferreira G. Vaginocervical stimulation of ewes induces the rapid formation of a new bond with an alien lamb without interfering with a previous bond. Developmental Psychobiology, 52(6): 537-544 (IF 1.891).
  15. Favreau A., Baumont R., Ferreira G., Dumont D. & Ginane C. Do sheep use umami and bitter tastes as cues of post-ingestive consequences when selecting their diet?. Applied Animal Behaviour Science, 125: 115-123 (IF 1.823).

  1. Wu K, Joffre C, Li X, Macveigh-Aloni M, Hom M, Hwang J, Ding C, Gregoire S, Bretillon L, Zhong JF, Hamm-Alvarez SF. Altered expression of genes functioning in lipid homeostasis is associated with lipid deposition in NOD mouse lacrimal gland. Exp Eye Res. 89: 319-332 (IF 2.579).
  2. Viau S, Maire MA, Pasquis B, Grégoire S, Acar N, Bron AM, Bretillon L, Creuzot-Garcher CP, Joffre C. Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model. Graefes Arch Clin Exp Ophthalmol 246: 857-67, (IF 1.770).
  3. Varon C, Duriez A, Lehours P, Ménard A, Layé S, Zerbib F, Mégraud F, Laharie D. Study of Helicobacter pullorum proinflammatory properties on human epithelial cells in vitro. Gut 58(5): 629-35 (IF 9.766).
  4. Van Waes V, Enache M, Zuena A, Mairesse J, Nicoletti F, Vinner E, Lhermitte M, Maccari S, Darnaudery M. Ethanol Attenuates Spatial Memory Deficits and Increases mGlu1a Receptor Expression in the Hippocampus of Rats Exposed to Prenatal Stress. Alcohol Clin Exp Res (IF 3.166).
  5. Sevelinges Y, Mouly A-M, Lévy F & Ferreira G. Long-term effects of infant learning on adult conditioned odor aversion are determined by the last preweaning experience. Developmental Psychobiology, in press (IF 1.89).
  6. Sevelinges Y, Lévy F, Mouly AM, & Ferreira G. Rearing with artificially scented mothers attenuates conditioned odor aversion in adulthood but not its amygdala dependency. Behavioural Brain Research 198: 313-320 (IF 3.17).
  7. Sevelinges Y, Desgranges B, & Ferreira G. The basolateral amygdala is necessary for encoding and expression of odor memory. Learning & Memory 16: 235-242 (IF: 4.12).
  8. Serra J, Ferreira G, Mirabito L, Lévy F & Nowak R. Post-oral and peri-oral stimulations during nursing enhances olfactory memory in neonatal rabbits. Chemical Senses, in press (IF 3.04).
  9. Schnebelen C, Viau S, Grégoire S, Joffre C, Creuzot-Garcher CP, Bron AM, Bretillon, L Acar N. Nutrition for the eye: different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation. Ophthalmic Res. 41: 216-224 (IF 1.317).
  10. Schnebelen C, Grégoire S, Pasquis B, Joffre C, Creuzot-Garcher CP, Bron AM, Bretillon L, Acar N. Dietary n-3 and n-6 PUFA enhance DHA incorporation in retinal phospholipids without affecting PGE (1) and PGE (2) levels. Lipids 44: 465-470 (IF 1.888).
  11. Schnebelen C, Grégoire S, Pasquis B, Joffre C, Creuzot-Garcher CP, Bron AM, Bretillon L, Acar N. A dietary combination of omega-3 and omega-6 polyunsaturated fatty acids is more efficient than single supplementations in the prevention of retinal damage induced by elevation of intraocular pressure in rats. Graefes Arch Clin Exp Ophthalmol: 247: 1191-1203 (IF 1.770).
  12. Palin K, Moreau ML, Sauvant J, Orcel H, Nadjar A, Duvoid-Guillou A, Dudit J, Rabie A, Moos F. Interleukin-6 Activates Arginine-Vasopressin Neurons in the Supraoptic Nucleus during Immune Challenge in Rats. Am J Physiol Endocrinol Metab. (IF 3.855)
  13. O'Connor JC, Lawson MA, André C, Moreau M, Lestage J, Castanon N, Kelley KW, Dantzer R. Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. Mol Psychiatry. 14(5): 511-22. (IF 12.54).
  14. O'Connor JC, Lawson MA, André C, Briley EM, Szegedi SS, Lestage J, Castanon N, Herkenham M, Dantzer R, Kelley KW. Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behavior. J Immunol. 182(5): 3202-12 (IF 6).
  15. O'Connor JC, André C, Wang Y, Lawson MA, Szegedi SS, Lestage J, Castanon N, Kelley KW, Dantzer R. Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin. J Neurosci. 29(13): 4200-9 ( (IF 7.45)
  16. Nadjar A, Gerfen CR, Bezard E. Priming for L-dopa-induced dyskinesia in Parkinson's disease: concepts and pathophysiology, Progress in Neurobiology 87(1): 1-9 (IF 9.130).
  17. Louvart H, Maccari S, Vaiva G, Darnaudery M. Prenatal stress exacerbates the impact of an aversive procedure on the corticosterone response to stress in female rats. Psychoneuroendocrinology 34: 786-790 (IF 3.788).
  18. Labrousse VF, Costes L, Aubert A, Darnaudery M, Ferreira G, Amédée T & Layé S. Impaired interleukin-1beta and c-Fos expression in the hippocampus is associated with spatial learning deficit in P2X7 receptor-deficient mice. PLoS ONE 4(6): e6006.
  19. Joffre C, Souchier M, Leclère M, Buteau B, Grégoire S, Lizard G, Montange T, Acar N, Bron AM, Creuzot-Garcher CP, Diebold Y, Bretillon L. Branched-chain fatty acids, increased in tears of blepharitis patients, are not toxic for conjunctival cells. Br J Ophthalmol, (IF 2.859)
  20. Gautron L, DeSmedt-Peyrusse V and Layé S. Age-related changes in nestin immunoreactivity in the rat pituitary gland, Neuroendocrinology 90(1): 19-30 (IF 2.295).
  21. Fourgeux C, Martine L, Björkhem I, Diczfalusy U, Joffre C, Acar N, Creuzot-Garcher C, Bron A, Bretillon L. Primary open angle glaucoma: association with cholesterol 24S-hydroxylase (CYP46A1) gene polymorphism and plasma 24-hydroxychoelsterol levels. Invest Ophthalmol Vis Sci., (IF 3.582).
  22. Desgranges B, Sevelinges Y, Bonnefond M, Ravel N, Lévy F & Ferreira G. Critical role of insular cortex in taste but not odor aversion memory. European Journal of Neuroscience 29: 1654-1662 (IF 3.38).
  23. Chapuis J, Garcia S, Messaoudi B, Thevenet M, Ferreira G, Gervais R & Ravel N. The way an odor is experienced during aversive conditioning determines the extent of the network recruited during retrieval: A multisite electrophysiological study in rats. The Journal of Neuroscience 29: 10287-10298. (IF 7.45)
  24. Capuron L, Moranis A, Combe N, Cousson-Gelie F, Fuchs D, De Smedt-Peyrusse V, Barberger-Gateau P, Layé S. Vitamin E status and quality of life in the elderly: influence of inflammatory processes. British Journal of Nutrition (IF 2.764).
  25. Capuron L, Fornwalt FB, Knight BT, Harvey PD, Ninan PT, Miller AH. Does cytokine-induced depression differ from idiopathic major depression in medically healthy individuals?Journal of Affective Disorders (IF 3.271).
  26. Bouvarel I, Chagneau A M, Lecuelle S, Lescoat P, Ferreira G, Duvaux-Ponter C & Leterrier C. Pellet composition and hardness interact in feed preference and intake in chickens. Applied Animal Behaviour Science 118: 62-68 (IF 1.82).
  27. Acar N, Berdeaux O, Juaneda P, Grégoire S, Cabaret S, Joffre C, Creuzot-Garcher CP, Bretillon L, Bron AM. Red blood cell plasmalogens and docosahexaenoic acid are independently reduced in primary open-angle glaucoma. Exp Eye Res, (IF 2.579).
  28. Nadjar A, Berton O, Guo S, Leneuve P, Dovero S, Diguet E, Tison F, Zhao B, Holzenberger M, BezardE. IGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP E.Neurobiol Aging. (IF5.959).
  29. Reese R, Charron G, Nadjar A, Aubert I, Thiolat ML, Hamann M, Richter A, Bezard E, Meissner WG. High frequency stimulation of the entopeduncular nucleus sets the cortico-basal ganglia network to a new functional state in the dystonic hamster.Neurobiol Dis 35(3):399-405 (IF4.852).

  1. Viau S, Maire MA, Pasquis B, Grégoire S, Fourgeux C, Acar N, Bretillon L, Creuzot-Garcher CP, Joffre C. Time course of ocular surface and lacrimal gland changes in a new scopolamine-induced dry eye model.Graefes Arch Clin Exp Ophthalmol 246: 857-67, (IF1.770).
  2. Souchier M, Joffre C, Grégoire S, Bretillon L, Muselier A, Acar N, Beynat J, Bron A, D'Athis P, Creuzot-Garcher C.Changes in meibomian fatty acids and clinical signs in patients with meibomian gland dysfunction after minocycline treatment.Br J Ophthalmol 92: 819-22 (IF2.859).
  3. Schuster S, Nadjar A, Guo JT, Li Q, Ittrich C, Hengerer B and Bezard E.The HMG-CoA Reductase Inhibitor Lovastatin reduces severity of l_dopa-induced abnormal involuntary movements in experimental Parkinson's disease,Journal of Neuroscience 28(17): 4311-6 (IF7.452).
  4. Samieri C, Jutand MA, Feart C, Capuron L, Letenneur L, Barberger-Gateau P.Dietary patterns derived by hybrid clustering method in older people: association with cognition, mood, and self-rated health.Journal of the American Dietetic Association 108(9): 1461-1471 (IF2.868).
  5. Moreau M, André C, O'Connor JC, Dumich SA, Woods JA, Kelley KW, Dantzer R, Lestage J, Castanon N. Inoculation of Bacillus Calmette-Guerin to mice induces an acute episode of sickness behavior followed by chronic depressive-like behavior.Brain Behav Immun. 22(7): 1087-95 (IF4.91).
  6. Miranda M, Rodriguez-Garcia G, Reyes J, Ferry B & Ferreira G.Differential effects of ß-adrenergic receptors blockade in basolateral amygdala or insular cortex on incidental and associative taste learning.Neurobiology of Learning & Memory, 90: 54-61. (IF3.76).
  7. Mingam R, Moranis A, Bluthé RM, De Smedt-Peyrusse V, Kelley KW, Guesnet P, Lavialle M, Dantzer R, Layé S. Uncoupling of interleukin-6 from its signalling pathway by dietary n-3-polyunsaturated fatty acid deprivation alters sickness behaviour in mice.Eur J Neuroscience 28(9): 1877-86 (IF3.385).
  8. Mingam R, De Smedt V, Amédée T, Bluthé RM, Kelley KW, Dantzer R, Layé S.In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1 beta in the murine brain.Brain Behav Immunology 22(2): 234-44 (IF4.90).
  9. Miller AH, Ancoli-Israel S, Bower JE, Capuron L, Irwin MR. Neuroendocrine-immune mechanisms of behavioral comorbidities in patients with cancer.Journal of Clinical Oncology 26 (6): 971-82 (IF17.157).
  10. Malvitte L, Montange T, Vejux A, Joffre C, Bron A, Creuzot-Garcher C, Lizard G. Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol.Curr Eye Res 33: 769-81 (IF1.519).
  11. Majer M, Welberg L, Capuron L, Pagnoni G, Raison CL, Miller AH.IFN-alpha-induced motor slowing is associated with increased depression and fatigue in patients with chronic hepatitis C.Brain Behavior and Immunity 22(6): 870-80 (IF4.909).
  12. Majer M, Welberg L, Capuron L, Miller AH, Pagnoni G, Reeves WC. Neuropsychological performance in persons with chronic fatigue syndrome: results from a population-based study.Psychosomatic Medicine 70(7): 829-836 (IF3.460).
  13. Lauzier B, Delemasure S, Debin R, Collin B, Sicard P, Acar N, Bretillon L, Joffre C, Bron A, Creuzot-Garcher C, Vergely C, Rochette L. Beneficial effects of myocardial postconditioning are associated with reduced oxidative stress in a senescent mouse model.Transplantation 85: 1802-8 (IF3.816).
  14. Joffre C, Souchier M, Grégoire S, Viau S, Bretillon L, Acar N, Bron AM, Creuzot-Garcher C. Differences in meibomian fatty acid composition in patients with meibomian gland dysfunction and aqueous-deficient dry eye.Br J Ophthalmol 92: 116-9 (IF2.859).
  15. Godbout JP, Moreau M, Lestage J, Chen J, Sparkman NL, O' Connor J, Castanon N, Kelley KW, Dantzer R, Johnson RW. Aging exacerbates depressive-like behavior in mice in response to activation of the peripheral innate immune system.Neuropsychopharmacology 33(10): 2341-51 (IF6.83).
  16. Enache M, Van Waes V, Vinner E, Lhermitte M, Maccari S, Darnaudery M. Impact of an acute exposure to ethanol on the oxidative stress status in the hippocampus of prenatal restraint stress adolescent male rats.Brain Res 1191: 55-62 (IF2.494).
  17. De Smedt-Peyrusse V, Sargueil F, Moranis A, Harizi H, Mongrand S, Layé S. Docosahexaenoic acid prevents lipopolysaccharide-induced cytokine production in microglial cells by inhibiting lipopolysaccharide receptor presentation but not its membrane subdomain localization.J Neurochem. 105(2): 296-307 (IF4.5).
  18. Desgranges B., Lévy F. & Ferreira G. Anisomycin infusion in amygdala impairs consolidation of odor aversion memory.Brain Research, 1236: 166-175. (IF2.49)
  19. Darnaudery M, Maccari S. Epigenetic programming of the stress response in male and female rats by prenatal restraint stress.Brain Res Rev 57:571-585 (IF6.236).
  20. Dantzer R, Capuron L, Irwin MR, Miller AH, Ollat H, Perry VH, Rousey S, Yirmiya R. Identification and treatment of symptoms associated with inflammation in medically ill patients.Psychoneuroendocrinology 33(1): 18-29 (IF3.788).
  21. Coyral-Castel S, Tosca L, Ferreira G, Jeanpierre E, Rame C, Lomet D, Caraty A, Monget P, Chabrolle C & Dupont J. The effect of AMPK activation on GnRH secretion in GT1-7 cells and its potential role in hypothalamic regulation of the oestrous cyclicity in rats.Journal of Neuroendocrinology, 20 (3): 335-346. (IF3.25)
  22. Capuron L, Su S, Miller AH, Bremner JD, Goldberg J, Vogt GJ, Maisano C, Jones L, Murrah NV, Vaccarino V. Depressive symptoms and metabolic syndrome: is inflammation the underlying link?Biological Psychiatry 64(10): 896-900 (IF8.672).
  23. Bretillon L, Thuret G, Grégoire S, Acar N, Joffre C, Bron AM, Gain P, Creuzot-Garcher CP. Lipid and fatty acid profile of the retina, retinal pigment epithelium/choroid, and the lacrimal gland, and associations with adipose tissue fatty acids in human subjects.Exp Eye Res 87: 521-528 (IF2.579).
  24. Bretillon L, Acar N, Seeliger MW, Santos M, Maire MA, Juanéda P, Martine L, Grégoire S, Joffre C, Bron AM, Creuzot-Garcher C. ApoB100, LDLR-/- mice exhibit reduced electroretinographic response and cholesteryl esters deposits in the retina.Invest Ophthalmol Vis Sci 49: 1307-14 (IF3.582).
  25. Bouvarel I, Vallée C, Chagneau A M, Constantin P, Lescoat P, Ferreira G & Leterrier C. Effects of various energy and protein levels during sequential feeding on feed preferences in meat-type chickens.Animal 2: 1674-1681. (IF0.99).
  26. André C, O'Connor JC, Kelley KW, Lestage J, Dantzer R, Castanon N. Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration.J Neuroimmunol. 30 200(1-2): 90-9. (IF3.16).

  1. Saint-Dizier H, Lévy F & Ferreira G. Influence of the mother in the development of flavored-food preference in lambs.Developmental Psychobiology 49 (1): 98-106 (IF1.89).
  2. Reese R, Winter C, Nadjar A, Harnack D, Bezard E, Kupsch A, Meissner W. Impact of High Frequency Stimulation on striatal Tyrosine Hydroxylase phosphorylation state.Neuroreport 19(2): 179-82 (IF2.333).
  3. Perrin G, Ferreira G, Meurisse M, Verdin S, Mouly A-M, & Lévy F. Social recognition memory requires protein synthesis after reactivation.Behavioral Neuroscience 121 (1): 148-155 (IF:2.59).
  4. Pasquereau B, Nadjar A, Arkadir D, Gouaillandeau M, Bioulac B, Gross CE, Boraud T. How the basal ganglia induce decision: Shaping of the motor response by the reward value.Journal of Neuroscience 27:1176-1183 (IF8.122).
  5. Miranda M, Ferry B & Ferreira G. Basolateral amygdala noradrenergic activity is involved in the acquisition of conditioned odor aversion in the rat.Neurobiology of Learning & Memory 88: 260-263 (IF:3.76).
  6. Mairesse J, Lesage J, Breton C, Breant B, Hahn T, Darnaudery M, Dickson SL, Seckl J, Blondeau B, Vieau D, Maccari S, Viltart O. Maternal stress alters endocrine function of the feto-placental unit in rats.Am J Physiol Endocrinol Metab 292: E1526-E1533 (IF3.855).
  7. Joffre C, Leclere L, Buteau B, Martine L, Cabaret S, Malvitte L, Acar N, Lizard G, Bron A, Creuzot-Garcher C, Bretillon L. Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells.Curr Eye Res. 32: 271-280 (IF1.519).
  8. Garcia-Segura LM, Diz-Chaves Y, Perez-Martin M, Darnaudery M. Estradiol, insulin-like growth factor-I and brain aging.Psychoneuroendocrinology 32 Suppl 1: S57-S61 (IF3.788).
  9. Frenois F, Moreau M, O'Connor J, Lawson M, Micon C, Lestage J, Kelley KW, Dantzer R, Castanon N. Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior.Psychoneuroendocrinology 32(5): 516-31 (IF3.79).
  10. Darnaudery M, Perez-Martin M, Del Favero F, Gomez-Roldan C, Garcia-Segura LM, Maccari S. Early motherhood in rats is associated with a modification of hippocampal function.Psychoneuroendocrinology 32: 803-812 (IF3.788).
  11. Darnaudery M, Louvart H, Defrance L, Leonhardt M, Morley-Fletcher S, Gruber SH, Galietta G, Mathe AA, Maccari S. Impact of an intense stress on ethanol consumption in female rats characterized by their pre-stress preference: modulation by prenatal stress.Brain Res 1131:181-186 (IF2.494).
  12. Chapuis J, Messaoudi B, Ferreira G & Ravel N. Importance of retronasal and orthonasal olfaction for odor aversion memory in rat.Behavioral Neuroscience 121(6): 1383-1392 (IF:2.59).
  13. Capuron L, Pagnoni G, Demetrashvili M, Lawson DH, Fornwalt F, Woolwine B, Berns GS, Nemeroff CB, Miller AH. Basal ganglia hypermetabolism and symptoms of fatigue during interferon-alpha therapy.Neuropsychopharmacology 32(11): 2384-92 (IF6.835).
  14. Canu MH, Darnaudery M, Falempin M, Maccari S, Viltart O. Effect of hindlimb unloading on motor activity in adult rats: impact of prenatal stress.Behav Neurosci 121: 177-185 (IF2.596).
  15. Bretillon L, Diczfalusy U, Bjorkhem I, Maire MA, Martine L, Joffre C, Acar N, Bron AM, Creuzot-Garcher CP.Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retina.Curr Eye Res. 32: 361-366 (IF1.770).
  16. Bezard E, Hoang CV, Potts BW, Pioli E, Kim KW, Nadjar A, Qin C, LaHoste GJ, Li Q, Bioulac BH, Gurevich E, Neve RL, Gold SJ. RGS9-2 negatively modulates L-dopa-induced dyskinesia in experimental Parkinson's disease,Journal of Neuroscience 27: 14338-48 (IF8.122).
  17. Acar N, Gregoire S, Andre A, Juaneda P, Joffre C, Bron A, Creuzot-Garcher C, Bretillon L. Plasmalogens in the retina: in situ hybridization of dihydroxyacetone phosphate acyltransferase (DHAP-AT) - the enzyme regulating their biosynthesis - and comparative study of retinal and retinal pigment epithelial lipid composition.Exp Eye Res. 84: 143-151 (IF2.579).

  1. Viltart O, Mairesse J, Darnaudery M, Louvart H, Vanbesien-Mailliot C, Catalani A, Maccari S. Prenatal stress alters Fos protein expression in hippocampus and locus coeruleus stress-related brain structures.Psychoneuroendocrinology 31: 769-780 (IF3.788).
  2. Van Waes V, Enache M, Dutriez I, Lesage J, Morley-Fletcher S, Vinner E, Lhermitte M, Vieau D, Maccari S, Darnaudery M. Hypo-response of the hypothalamic-pituitary-adrenocortical axis after an ethanol challenge in prenatally stressed adolescent male rats.Eur J Neurosci 24: 1193-1200 (IF3.85).
  3. Raison CL, Capuron L, Miller AH. Cytokines sing the blues: inflammation and the pathogenesis of depression.Trends in Immunology 27: 24-31 (IF9.910).
  4. Nadjar A, Brotchie JM, Guigoni C, Qin Li, Shao-Bo Zhou, Gui-Jie Wang, Ravenscroft P, Georges F, Crossman AR and Bezard E. Phenotype of striatofugal medium spiny neurons in parkinsonian and dyskinetic non-human primates: a call for a reappraisal of the functional organization of the basal ganglia,Journal of Neuroscience 26(34): 8653-8661 (IF8.122).
  5. Malvitte L, Montange T, Joffre C, Vejux A, Maiza C, Bron A, Creuzot-Garcher C, Lizard G. Analogies between atherosclerosis and age-related maculopathy: expected roles of oxysterols.J Fr Ophtalmol. 29: 570-578 (IF0.450).
  6. Louvart H, Maccari S, Lesage J, Leonhardt M, ckes-Coopman A, Darnaudery M. Effects of a single footshock followed by situational reminders on HPA axis and behaviour in the aversive context in male and female rats.Psychoneuroendocrinology 31: 92-99 (IF3.788).
  7. Kappeler L, Gautron L, Layé S, Dantzer R, Zizzari P, Epelbaum J and Bluet-Pajot MT. Pituitary CART expression depends on the rat strain and nutritional hormone levels,J. Neuroendocrinology 18 426-433 (IF3.252).
  8. Gautron L, De Smedt V and Layé S. Characterization of STAT3-expressing cells in the postnatal brain.Brain Research 1098: 26-32 (IF2.494).
  9. Ferry B., Ferreira G, Traissard N, & Majchrzak M. Selective involvement of the lateral entorhinal cortex in the control of the olfactory memory trace during conditioned odor aversion in the rat.Behavioral Neuroscience 120(5): 1180-1186 (IF:2.59).
  10. Ferreira G, Ferry B, Meurisse M & Lévy F. Forebrain structures specifically activated by conditioned taste aversion.Behavioral Neuroscience 120(4): 952-962 (IF:2.59).
  11. Darnaudery M, Perez-Martin M, Belizaire G, Maccari S, Garcia-Segura LM. Insulin-like growth factor 1 reduces age-related disorders induced by prenatal stress in female rats.Neurobiol Aging 27: 119-127 (IF5.959).
  12. Creuzot C, Passemard M, Viau S, Joffre C, Pouliquen P, Elena PP, Bron A, Brignole F. Improvement of dry eye symptoms with polyunsaturated fatty acids.J Fr Ophtalmol. 29: 868-873 (IF0.450).
  13. Capuron L, Welberg L, Heim C, Wagner D, Solomon L, Papanicolaou D, Craddock RC, Miller AH, Reeves WC. Cognitive dysfunction relates to subjective reports of mental fatigue in patients with chronic fatigue syndrome.Neuropsychopharmacology 31(8): 1777-1784 (IF6.835).
  14. Akirav I, Khatsrinov V, Vouimba RM, Ferreira G, Rosenblum K, Maroun M. Extinction of conditioned taste aversion depends on functional protein synthesis but not on NMDA receptor activation in the ventromedial prefrontal cortex.Learning & Memory 13: 254-258 (IF:4.12).
  15. Acar N, Bonhomme B, Joffre C, Bron A, Creuzot-Garcher C, Bretillon L, Doly M, Chardigny JM. The retina is more susceptible than the brain and the liver to the incorporation of trans isomers of DHA in rats consuming trans isomers of alpha-linolenic acid.Reprod Nutr Dev. 46: 515-525 (IF2.167).

  1. Raison CL, Demetrashvili M, Capuron L, Miller AH. Neuropsychiatric adverse effects of Interferon-alpha: recognition and management.CNS Drugs 19: 105-123 (IF4.432).
  2. Raison CL, Broadwell SD, Borisov AS, Manatunga AK, Capuron L, Woolwine BJ, Jacobson IM, Nemeroff CB, Miller AH. Depressive symptoms during IFN-alpha/ribavirin therapy are associated with reduced viral clearance in patients with hepatitis C.Brain Behavior and Immunity 19(1): 23-27
  3. Raison CL, Borisov AS, Broadwell SD, Capuron LC, Woolwine BJ, Jacobson IM, Nemeroff CB, Miller AH.Depression during pegylated IFN-alpha plus ribavirin therapy: prevalence and prediction.Journal of Clinical Psychiatry 66(1): 41-48 ((IF5.053).
  4. Nadjar A, Tridon V, May MJ, Ghosh S, Dantzer R, Amedee T and Parnet P. NFkappaB activates in vivo the synthesis of inducible but not constitutive Cox-2 in the brain.Journal of Cerebral Blood Flow and Metabolism 25(8): 1047-59 IF (IF5.74).
  5. Nadjar A, Combe C, Busquet P, Dantzer R, Parnet P. Signaling pathways of interleukin-1 actions in the brain: anatomical distribution of phospho-ERK1/2 in the brain of rat treated systemically with interleukin-1ß,Neuroscience 134(3): 921-32. (IF3.440).
  6. Nadjar A, Bluthé RM, May MJ, Dantzer R and Parnet P. Inactivation of the cerebral NFkappaB pathway inhibits interleukin-1ß-induced sickness behavior and c-Fos expression in various brain nuclei.Neuropsychopharmacology 30(8): 1492-9 (IF5.369).
  7. Moreau M, Lestage J, Verrier D, Mormede C, Kelley KW, Dantzer R, Castanon N. Bacille Calmette-Guérin inoculation induces chronic activation of peripheral and brain indoleamine 2,3-dioxygenase in mice.J Infect Dis. 192(3): 537-44. (IF5.68).
  8. Miller AH, Capuron L, Raison CL. Immunologic influences on emotion regulation.Clinical Neuroscience Research 4: 325-333 (IF1.469).
  9. Louvart H, Maccari S, Ducrocq F, Thomas P, Darnaudery M. Long-term behavioural alterations in female rats after a single intense footshock followed by situational reminders.Psychoneuroendocrinology 30: 316-324 (IF3.788).
  10. Louvart H, Maccari S, Darnaudery M. Prenatal stress affects behavioral reactivity to an intense stress in adult female rats.Brain Res 1031:67-73 (IF2.494).
  11. Gautron L, Mingam R, Moranis A, Combe C, Layé S. Influence of feeding status on neuronal activity in the hypothalamus during lipopolysaccharide-induced anorexia in rats.Neuroscience 134 933-46 (IF3.556).
  12. Ferreira G, Miranda MI, De la Cruz V, Rodriguez-Ortiz CJ & Bermudez-Rattoni F. Basolateral amygdala glutamatergic activation enhances taste aversion through NMDA receptor activation in the insular cortex.European Journal of Neuroscience 22(10): 2596-2604 (IF3.38).
  13. Capuron L, Pagnoni G, Demetrashvili M, Woolwine BJ, Nemeroff CB, Berns GS, Miller AH. Anterior cingulated activation and error processing during interferon-alpha treatment.Biological Psychiatry 58(3): 190-196 (IF8.672).
Chronic Low-Grade Inflammation in Elderly Persons

"Chronic Low-Grade Inflammation in Elderly Persons Is Associated with Altered Tryptophan and Tyrosine Metabolism: Role in Neuropsychiatric Symptoms" in Biol Psychiatry. 2011 Jan 28

Capuron L, Schroecksnadel S, Féart C, Aubert A, Higueret D, Barberger-Gateau P, Layé S, Fuchs D
Read more