Know more

About cookies

What is a "cookie"?

A "cookie" is a piece of information, usually small and identified by a name, which may be sent to your browser by a website you are visiting. Your web browser will store it for a period of time, and send it back to the web server each time you log on again.

Different types of cookies are placed on the sites:

  • Cookies strictly necessary for the proper functioning of the site
  • Cookies deposited by third party sites to improve the interactivity of the site, to collect statistics

Learn more about cookies and how they work

The different types of cookies used on this site

Cookies strictly necessary for the site to function

These cookies allow the main services of the site to function optimally. You can technically block them using your browser settings but your experience on the site may be degraded.

Furthermore, you have the possibility of opposing the use of audience measurement tracers strictly necessary for the functioning and current administration of the website in the cookie management window accessible via the link located in the footer of the site.

Technical cookies

Name of the cookie

Purpose

Shelf life

CAS and PHP session cookies

Login credentials, session security

Session

Tarteaucitron

Saving your cookie consent choices

12 months

Audience measurement cookies (AT Internet)

Name of the cookie

Purpose

Shelf life

atid

Trace the visitor's route in order to establish visit statistics.

13 months

atuserid

Store the anonymous ID of the visitor who starts the first time he visits the site

13 months

atidvisitor

Identify the numbers (unique identifiers of a site) seen by the visitor and store the visitor's identifiers.

13 months

About the AT Internet audience measurement tool :

AT Internet's audience measurement tool Analytics is deployed on this site in order to obtain information on visitors' navigation and to improve its use.

The French data protection authority (CNIL) has granted an exemption to AT Internet's Web Analytics cookie. This tool is thus exempt from the collection of the Internet user's consent with regard to the deposit of analytics cookies. However, you can refuse the deposit of these cookies via the cookie management panel.

Good to know:

  • The data collected are not cross-checked with other processing operations
  • The deposited cookie is only used to produce anonymous statistics
  • The cookie does not allow the user's navigation on other sites to be tracked.

Third party cookies to improve the interactivity of the site

This site relies on certain services provided by third parties which allow :

  • to offer interactive content;
  • improve usability and facilitate the sharing of content on social networks;
  • view videos and animated presentations directly on our website;
  • protect form entries from robots;
  • monitor the performance of the site.

These third parties will collect and use your browsing data for their own purposes.

How to accept or reject cookies

When you start browsing an eZpublish site, the appearance of the "cookies" banner allows you to accept or refuse all the cookies we use. This banner will be displayed as long as you have not made a choice, even if you are browsing on another page of the site.

You can change your choices at any time by clicking on the "Cookie Management" link.

You can manage these cookies in your browser. Here are the procedures to follow: Firefox; Chrome; Explorer; Safari; Opera

For more information about the cookies we use, you can contact INRAE's Data Protection Officer by email at cil-dpo@inrae.fr or by post at :

INRAE

24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo Principal NutriNeurO logo partenaire Logo Bx INP

NutriNeuro: Integrated Nutrition and Neurobiology Lab

Zone de texte éditable et éditée et rééditée

NutriPsy: Nutrition and Neuropsychiatric symptom dimensions

NutriPsy

Leader: Lucile Capuron, DR1 INRAE lucile.capuron@inrae.fr

Deputy leader: Marie-Pierre Moisan, DR2 INRAE marie-pierre.moisan@inrae.fr

Team presentation

The overarching scientific objective of the Nutripsy team is to understand how nutrition can contribute to mental health, and to identify the mechanisms by which nutritional imbalances promote the development of neuropsychiatric symptoms, focusing on inflammatory processes. For this purpose, we propose a translational and integrative research program with the following complementary specific aims: 

i)               to elucidate the mechanisms by which inflammation, in relation to dietary habits, leads to neuropsychiatric symptom dimensions and antidepressant resistance 

ii)              to determine the influence of environmental factors and genetic variants related to inflammation on depressive symptoms and antidepressant response in clinical and preclinical models of nutritional imbalances, 

iii)              to propose innovative personalized treatment strategies through targeted nutritional approaches guided by the clinical, biological/inflammatory, and nutritional profiles of patients. 

This research program represents a critical step toward a precision medicine applied to mental health, in a context where the efficacy of standard treatments remains mitigated.

Research axes

Axe 8: Nutrition and Mental Health

Axe 6: Psychiatric Pathologies

Researchers

Nathalie Castanon (Chargée de recherche INRAE) 

Muriel Darnaudery (Professeure) 

Sylvie Vancassel (Chargée de recherche INRAE)

Clinicians

Bruno Aouizerate (Professeur Universitaire - Praticien hospitalier) 

Pascal Barat (Professeur Universitaire - Praticien hospitalier) 

Julie Brossaud (Maître de conférences Universitaire - Praticien hospitalier) 

Jean-Benoît Corcuff (Maître de conférences Universitaire - Praticien hospitalier) 

Alexandra Bouvard (Praticien hospitalier Université de Bordeaux) 

Hélène Thibault (Praticien hospitalier Université de Bordeaux) 

Julie Bernard (CCA Université de Bordeaux)

Technicians - Engineers

Sandra Dexpert (AI INRAE)

Aline Foury  (IE INRAE)

Jean-Christophe Helbling (IE INRAE)

Post-docs

Sofia Cussotto (Post-doctorante)

Doctorants

Juliette Montet

Publications

A new experimental design to study inflammation-related versus non-inflammation-related depression in mice. Cardinal P, Monchaux de Oliveira C, Sauvant J, Foury A, Darnaudéry M, Vancassel S, Castanon N, Capuron L.J Neuroinflammation. 2021 Dec 11;18(1):290. 

 

Influence of pro-obesogenic dietary habits on stress-induced cognitive alterations in healthy adult volunteers. Delgado I, Dexpert S, Sauvant J, Cryan JF, Capuron L.

Neurobiol Stress. 2021 Jun 12;15:100353. doi: 10.1016/j.ynstr.2021.100353. eCollection 2021 Nov.

 

Transcriptomic signaling pathways involved in a naturalistic model of inflammation-related depression and its remission.Moisan MP, Foury A, Dexpert S, Cole SW, Beau C, Forestier D, Ledaguenel P, Magne E, Capuron L.Transl Psychiatry. 2021 Apr 6;11(1):203.

 

Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission. Monchaux De Oliveira C, Pourtau L, Vancassel S, Pouchieu C, Capuron L, Gaudout D, Castanon N.Nutrients. 2021 Mar 11;13(3):904.

 

Relationship between body mass index and neuropsychiatric symptoms: Evidence and inflammatory correlates. Huet L, Delgado I, Dexpert S, Sauvant J, Aouizerate B, Beau C, Forestier D, Ledaguenel P, Magne E, Capuron L. Brain Behav Immun. 2021 May;94:104-110. 

Special Issue: The intersection of inflammation and metabolism in neuropsychiatric disorders. Felger JC, Capuron L.Brain Behav Immun. 2021 Mar;93:331-334. 

 

Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner. Rincel M, Aubert P, Chevalier J, Grohard PA, Basso L, Monchaux de Oliveira C, Helbling JC, Lévy É, Chevalier G, Leboyer M, Eberl G, Layé S, Capuron L, Vergnolle N, Neunlist M, Boudin H, Lepage P, Darnaudéry M.Brain Behav Immun. 2019 Aug;80:179-192

 

Brain tumor necrosis factor-α mediates anxiety-like behavior in a mouse model of severe obesity. Fourrier C, Bosch-Bouju C, Boursereau R, Sauvant J, Aubert A, Capuron L, Ferreira G, Layé S, Castanon N.Brain Behav Immun. 2019 Mar;77:25-36. 

 

Inflammatory bases of neuropsychiatric symptom domains: mechanisms and specificity. Aouizerate, B., Vancassel, S., Castanon, N., Capuron, L., 2021 In: Immuno-Psychiatry. Facts and prospects. M. Berk, M. Leboyer, I. E. Sommer (eds), Springer, chapter 20, pp 335-353.

 

Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry. 

Fanet H, Capuron L, Castanon N, Calon F, Vancassel S.Curr Neuropharmacol. 2021;19(5):591-609. Review.