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Last update: May 2021

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UR 1264 - MYCSA : Mycologie et securite des aliments


Mycologie & Sécurité des Aliments
INRA Bordeaux-Aquitaine
BP 81
33883 Villenave d'Ornon Cedex

Rat feeding trials: A comprehensive assessment of contaminants in both genetically modified maize and resulting pellets

02 October 2018

GM-Maize contaminants
Our new article published in Food and Chemical Toxicology

Chéreau S., Rogowsky P., Laporte B., Coumoul X., Moing A., Priymenkoc N., Steinberg P., Wilhelm R., Schiemann J., Salles B., Richard-Forget F. (2018). Rat feeding trials: A comprehensive assessment of contaminants in both genetically modified maize and resulting pellets. Food and Chemical Toxicology 121: 573–582.

Open access before November 20, 2018:

Abstract :

We analyzed a comprehensive set of contaminants in MON810 and NK603 genetically modified (GM) maize, and their non-GM counterparts, used in a rat feeding study (the GMO90 + project). Both the maize grains and the manufactured pellets were characterized. Only minor differences in contaminant levels between GM and corresponding non-GM harvests were evidenced. Fumonisin and deoxynivalenol mycotoxins were the pollutants present in the highest amounts, with concentrations that were however largely below acceptance reference values. Our data reporting slightly lower levels of fumonisin in MON810 compared to its non-GM counterpart corroborate the lower susceptibility of insect resistant Bt maize to fumonisin-producing fungi. Traces of glyphosate (0.016 mg/kg) were evidenced in grains from NK603 treated crops. Regarding the pellets, analysis of more than 650 potentially toxic substances revealed low amounts of various mycotoxins, pesticides and heavy metals. Concentrations of contaminants quantified in the pellets were however far below the maximum level of residues values set by regulatory agencies, and no substantial differences in contaminants between GM and non-GM pellets were observed. Moreover, when comparing the contamination status of grains and pellets, we demonstrate yet again that characterizing the grains is actually not sufficient to foresee the quality of the produced pellets.